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Tuesday, 06 June
01:00
Read This Before 3D Scanning In A Museum "IndyWatch Feed Diy"
Scanning in museums is the perfect challenge for the photogrammetry hobbyist. Not all museums have in-house scanning programs, but its important to archive and share these objects with people all over the world. You can help make it happen. Photogrammetry is the process of converting hundreds of photos into a 3D model. The principles of 3D scanning []
The post Read This Before 3D Scanning In A Museum appeared first on Make: DIY Projects and Ideas for Makers.
00:56
Bitcoin price will get 'another test' of 200-week trend line analyst "IndyWatch Feed Crypto"
A crucial BTC price support is coming back into the picture with Bitcoin bulls struggling below $27,000.
00:45
Shockingly Complete 1,100-Year-Old Hebrew Bible (aka Tanakh) Sells for Over $38 Million "IndyWatch Feed Arts"
Shockingly Complete 1,100-Year-Old Hebrew Bible (aka Tanakh) Sells for Over $38 Million
The Codex Sassoon. (Photo: Sotheby's)
The Hebrew Bible is a foundational text of human history, no matter your religion or belief in its contents. A sacred text, known as Tanakh, it comprises 24 books including the five books of Moses. Jewish, Christian, and Muslim sacred texts are either derived from or influenced by this ancient text. This incredibly special, early 10th-century manuscript is one of the most complete and ancient Bibles, explaining why it recently fetched over $38 million at auction.
The volume is known as the Codex Sassoonnamed after its 1929 purchaser, David Solomon Sassoon, a collector of Jewish manuscripts. The binding is modern and carries Sassoon's crest on the interior plate. Bound within are 792 pages weighing a whopping 26 pounds. Only 12 leaves of the text are missing. Some portions of pages have been lost to time and new pieces stitched in, the text carefully recopied. Most fascinating is the marginalia, known as Masorah notes. The Masorah parva, miniscule text which was quite abbreviated, and the Masorah magna, usually at the top and bottom margins. Both types of Masorah notes were aids to scholars and scribes replicating the Tanakh by hand. These notes indicated textual features and where they were repeated throughout the volume, to ensure the preservation of the true text.
The Sassoon Codex fills an important niche in Jewish, and human, history. The Dead Sea Scrolls date at their latest to the first century CE. The Aleppo Codexwhich is mentioned by the Sassoon textwas created around 930....
00:16
Privacy Concerns Dominate CBDC Discussion at Consensus 2023 "IndyWatch Feed Crypto"
U.S. government whistleblower and Nym Technologies consultant Chelsea Manning discusses cryptography and cryptocurrency on stage at Consensus 2023 with CoinDesk Executive Editor Marc Hochstein. (Shutterstock/CoinDesk)
00:15
Introducing CoinDesks First-Ever Consensus @ Consensus Report "IndyWatch Feed Crypto"
Consensus Executive Editor Marc Hochstein interviewed Nym Technologies security consultant and U.S. government whistleblower Chelsea Manning at CoinDesk's Consensus 2023 conference. (Shutterstock/CoinDesk)
00:13
El Salvador's Volcano Energy Secures $1B in Commitments For 241 MW Bitcoin Mine "IndyWatch Feed Crypto"
The top of the City Hall of Santa Ana city, El Salvador. (Getty Images)
00:11
Binance Executive Controlled Bank Accounts Belonging to U.S. Wing in 2019-20: Reuters "IndyWatch Feed Crypto"
Binance (Danny Nelson/CoinDesk)
00:00
New Stablecoin Issuer Raft Is Eschewing Fiat for Its Financial Backing "IndyWatch Feed Crypto"
(Alfred Gescheidt/Getty Images)
Monday, 05 June
23:50
Surreal Stretchy Ceramic Pots Imagine Souls Trying To Escape From Within "IndyWatch Feed Arts"
Surreal Stretchy Ceramic Pots Imagine Souls Trying To Escape From Within
This post may contain affiliate links. If you make a purchase, My Modern Met may earn an affiliate commission. Please read our disclosure for more info.
Artist Jackson Shaner creates pottery that borders on terrifying. His surreal vessels appear as the keeper of souls, and those souls are trying to escape. The screaming faces and tiny hands attempt to break the confines of the pots, stretching the sides and showcasing the vessels' malleable strength. (The pots, after all, are strong enough to contain the force of these beings.) The resulting pieces are frightening yet thought-provoking and invite us to consider who and what is inside.
The inspiration for Shaners work lies in classical sculpture, contemporary ceramics, fantasy, and horror. I make pots that act as metaphors for emotional containment, he tells My Modern Met, how I tend to ball up emotions and hold them in, only allowing myself to release and be vulnerable in specific circumstances.
The vessels, a combination of wheel-throwing and sculpture, have a double meaning. They hold physical objects as well as the intangible. Shaner's primary interest lies in what we cannot see. My work deals with themes of containment, struggle, and somatization: how emotions can create physical sensations of discomfort, tension, and even pain.
Shaner pours himself into every part of the process. [It] is extremely cathartic and empowering as it allows my emotions to take up, and activate space. Although the work is personal, the viewer is an important component. I enjoy hearing viewers' diverse interpretations, as I believe they bring new energy and meaning to my work.
Shaner sells his work on his Instagram...
23:36
Help stop two bad vaccines bill in the New Jersey Legislature! "IndyWatch Feed Food"
New Jersey Legislative Bills A. 5445 and S. 3841 would trivialize very real vaccine risks and serious reactions by allowing optometrists to vaccinate.
Previously, under the Emergency Health Powers Act, optometrists were allowed to administer immunizations against a coronavirus or influenza during a public health emergency involving an outbreak or epidemic limited to administering immunizations against the specific disease for which the public health emergency was declared. Those receiving vaccines from optometrists had to be 18 years or older and the records were required to be reported to the New Jersey Immunization Information System for inclusion in the patients registry.
A. 5445 and S. 3841 would:
- Remove the public health emergency requirement for optometrist vaccine administration
- Allow optometrists to administer vaccines to patients over 18 years old even when no public health emergency is declared
- Expand the number of vaccines optometrists are able to give by adding the varicella-zoster vaccines to the list of vaccines optometrists can give
- Continue to require that all immunization records be reported to the New Jersey Immunization Information System for inclusion in the patients registry
All immunization records would be forwarded to the state vaccine database tracking system.
Any time optometrists are allowed to vaccinate, it creates significant risks. Optometrists are not qualified to recognize or handle serious adverse reactions, nor are they likely to have full knowledge of patient or family history.
The Weston A. Price Foundation does not take a position on other sections of the bill dealing strictly with eye care procedures.
Please speak up!
TAKE ACTION
- Contact your New Jersey State Senator and two Assembly Members and urge them to oppose A. 5445 and S. 3841.
You can look up who represents you here:
By municipality: http://www.njleg.state.nj.us/districts/municipalities.asp
Interactive map: http://www.njleg.state.nj.us/districts/njmap210.html
Calls are more effective than emails and only take a few minutes. Below is a sample script along with additional Talking Points. Use your own words when you call or email a personal message is always more effective than a form message!
SAMPLE SCRIPT:
Hi, my name is ____ and I am a constituent. I am calling to ask Senator (or Assembly Member) ____ to oppose A. 5445 and S. 3841, which would allow optometrists to administer vaccines.
I...
23:35
Hong Kongs regulatory lead sets it up to be major crypto hub "IndyWatch Feed Crypto"
Hong Kong is increasingly solidifying its status as a crypto hub in Asia despite most other countries taking a cautious approach.
23:32
El Salvador Unleashes "Volcano Energy" With 241 Megawatt Planned Bitcoin Mining Operation "IndyWatch Feed Crypto"
The country of El Salvador is tapping into its abundant natural resources to create Volcano Energy. According to a press release sent to Bitcoin Magazine, the aim is to position the country as a major global player in the Bitcoin mining industry while promoting energy competitiveness, diversification and geographic expansion for the Bitcoin network. Adopting a debt-free approach, El Salvador plans to construct a 241 megawatt (MW) renewable power generation park in the Metapn region, combining solar and wind projects.
"This project is a transformative journey that will establish one of the world's largest Bitcoin mining farms," the release said. Located in the El Shiste hamlet, within the municipality of Metapn, Santa Ana, this chosen site boasts exceptional solar and wind energy yields in the country. The park will have a capacity of 169MW of photovoltaic solar energy and 72MW of wind energy. The initial computational power is expected to surpass 1.3 EH/s, marking a significant milestone for the country and industry.
The release stated that The total commitment for the project is $1 billion, beginning with a first investment of $250 million, bootstrapped by key Bitcoin industry leaders, with collaboration from top developers and manufacturers of renewable energy technology, as well as Bitcoin mining experts on a global scale. The government of El Salvador will play a crucial role in the planning and execution of the initiative, securing a preferred participation equivalent to 23% of the revenue. The remaining ownership will be divided among investors and reinvested in expanding energy production capacity and advancing Bitcoin mining.
Robert Warren of Distributed Hash explained on Twitter that the reasoning behind leveraging wind and solar is likely to monetize quicker to build upon a base set of geothermal expansion.
By leveraging Volcano Energy, El Salvador aims to create a prosperous future driven by sustainable energy and Bitcoin. As the countrys investment progresses volcanoes could serve as the backbone of this transformation, fostering economic growth and prosperity for future generations. The establishment of the renewable power generation park signifies a large step towards achieving these goals while cementing El Salvador's position in the global Bitcoin mining industry.
23:30
Consumer loyalty is waning: Web3 could bring it back "IndyWatch Feed Crypto"
Understanding and nurturing fan loyalty may be even more essential in the sporting world than in most industries.
23:25
First Mover Americas: Is Bitcoin Heading Below $26K? "IndyWatch Feed Crypto"
The latest price moves in bitcoin (BTC) and crypto markets in context for June 5, 2023. First Mover is CoinDesks daily newsletter that contextualizes the latest actions in the crypto markets.
23:20
The transformative impact of Warhol v. Goldsmith "IndyWatch Feed Arts"
WAS THAT REASONABLY NECESSARY? Its a question asked every day in law schools and courthouses. Less so in MFA programs, artist studios, and museum acquisition committee meetings. Imagine counsel
23:19
3 Reasons Why Beauty on the Blockchain Makes Sense "IndyWatch Feed Crypto"
(Colin Anderson/Getty Images)
23:17
A Woman Explained Why Millennials Are So Awkward in Photos and It Got People Talking "IndyWatch Feed Arts"
Those poor Millennials just cant catch a break, can they?
Theyre the butt of a lot of jokes and now theyre catching a whole lot of grief for being awkward in photographsgood grief!
And a posing expert (yes, you read that right) named Christine Buzan has a guide called 101 Ways to Pose so you can take her advice to heartand she thinks she knows whats going on with these Millennials and why theyre awkward in photos.
Buzan posted a video on TikTok where she talked about her theory.
Photo Credit:...
23:15
Are Web3 apps under scrutiny? "IndyWatch Feed Crypto"
One of the biggest challenges Web3 apps are facing is the difficulty of reaching a wider audience.
23:08
23:02
This Draconian Slave Ship Matrix Veil has cracked "IndyWatch Feed Uncanny"
This Draconian Slave Ship Matrix Veil has cracked we have reached the EVENT HORIZON. The moment we have battled for has come to fruition, the MSM has been forced Continue Reading
Het bericht This Draconian Slave Ship Matrix Veil has cracked verscheen eerst op Take care 4.
23:00
Tim Griffin to Lead LA Opera Company the Industry "IndyWatch Feed Arts"
Los Angelesbased experimental opera producer the Industry has announced Tim Griffin as its next executive director. Griffin, a former editor-in-chief of Artforum and onetime director of the Kitchen,
DeFi aggregation: Paving the way for mass adoption "IndyWatch Feed Crypto"
The DeFi revolution is transforming our financial landscape and empowering everyday people to take back control over their assets.
22:57
SkyView Astrology: Full Moon Reading 5 June 23 Find roots in your spirituality! "IndyWatch Feed Spiritual"
The link to the Matthew Message: https://www.matthewbooks.com/june-1-2023/
Europa, the last battle 2017 - Full documentary HD
https://www.bitchute.com/video/s1nPYDj7KBEQ/ For those
new to my readings, please check out the latest Introduction
because it is quite different from the Western/Tropical Astrology
and my previous reading in my blog page: A guide to Lifes
Pilgrimage and the Souls Path of Evolution https://skyviewastrology.wordpress.com/2020/12/14/a-guide-to-lifes-pilgrimage-and-the-souls-path-of-evolution/...22:45
EU officials want all AI-generated content to be labeled "IndyWatch Feed Crypto"
European Commission Vice President, Vera Jourova, said that companies deploying generative AI tools with the potential to spread disinformation should be publicly labeled.
22:40
US Navy And NASA Have A Fully Operational Space Fleet "IndyWatch Feed Spiritual"
In addition to this unusual roster of names, McKinnon also found listings for a secret space fleet, around ten warships all pre-fixed with the title USS.
It is McKinnons belief that this flotilla of secret space ships are being operated by the United States government and are fully staffed with military personnel.
22:00
Weve Failed Gen Z, But Bitcoin Offers Hope For The Future "IndyWatch Feed Crypto"
This is an opinion editorial by David Waugh, business development and communications specialist at bitcoin investing platform Coinbits, and Dave Birnbaum, the product director at Coinbits.
Every generation has bones to pick with those who came before. However, Generation Z, those born between the late 1990s and early 2010s, have an especially valid complaint: Previous generations have stolen their future.
Also called the Zoomers, this group was forced by lockdowns and school closures to socialize through webcams during their formative years. These 68 million Americans have had their lives disrupted by social upheaval, wealth destruction and cultural decline, all during the prime of their youth.
Many Zoomers do not yet realize the scale of the crime perpetrated against them. Some are waking up. Either way, all of them will soon need to chip in to pay the piper for decades of monetary and fiscal mismanagement by prior generations.
But the situation is not hopeless. There is a tool that Generation Z can use to achieve restitution. Instead of embarking on a dismal project to rebuild our ruined financial system, only to reinstate the rents and inequities that existed before, Zoomers can leave their mark upon history by using bitcoin to build a new system that is resilient, equitable and just.
Like the Greatest Generation, which rebuilt America on strong foundations after facing down the greatest threat to humanity that had ever manifested, Generation Z can channel their well-earned sense of betrayal and loss to create a world order worthy of being passed down to their own children and grandchildren.
Backed Into A Corner
Sometimes called the loneliest generation, Gen Z has been sold out by their elders, who have declined to make the necessary sacrifices to allow future generations to prosper. The psychological warfare waged against Zoomers is sometimes subtle, but often, it is not. In schools, mass media and online, they are assailed with doom about climate, race and exploitation, and told that their future has been stolen by evil people who selfishly refuse to fix those problems.
In fact, this is a half truth. The Zoomers' future has indeed been stolen, but not by polluters and racists. Instead, globalist elites, smart enough to see their system failing but not courageous enough to take responsibility for it, have looted the financial and cultural capital left to us by the Greatest Generation.
As part of the coverup for this crime, Zoomers have endured a constant onslaught of depressing propaganda. They are told the world will end in 10 year...
21:58
It never ends folks.. the quest for the governments to provide TRUTH! "IndyWatch Feed Spiritual"
So Many Wrongdoers Hiding Truth!
This Requires Judicial Assistance! IOJ Is On It!
HHS and DoD can count themselves in as defendants for hiding reports about the DoD military rollout of the "The Experimental Biological Agent Covid-19 Vaccine" they said they would give us a month ago. The HHS will not even respond to a password Request Change Within The HHS FOIA Department.21:47
happy pride month from gary varvel. "IndyWatch Feed Comics"
happy pride month from gary varvel.
21:40
The blockchain and AI bond, explained "IndyWatch Feed Crypto"
Discover the potential of combining blockchain and AI for enhanced transparency, privacy, collaboration and innovation in various industries.
21:10
21:01
Defunct Crypto Hedge Fund 3AC Insists on Taking Part in Genesis Mediation "IndyWatch Feed Crypto"
Three Arrows Capital has made claims against Genesis (aitoff/Pixabay)
21:01
20:50
JPMorgan uses blockchain for 24/7 dollar transfers with Indian banks "IndyWatch Feed Crypto"
JPMorgan applies blockchain to interbank U.S. dollar transactions in India amid growing signs of global de-dollarization.
20:40
Crypto Tsar needed to ensure coordinated approach in the UK: EU lawmakers "IndyWatch Feed Crypto"
APPG chair Lisa Cameron emphasized the reports significance in securing the U.K.s leadership in the crypto sector and safeguarding consumers.
20:35
Mom Wonders If She Went Too Far In Trying To Force Her Teen Daughter To Learn ASL "IndyWatch Feed Arts"
There is no doubt that blending families is difficult and thats when all parties involved are actually intent on trying to make the best of the situation.
When someone is determined to make life miserable for everyone else, what do you do?
OP had been widowed with a young daughter for over a decade when she met someone she felt serious about. As he had a young daughter who is deaf, she took it upon herself to learn ASL so they would be able to communicate.
I (49 F) recently married my husband (52M) who has a deaf 7 year old daughter. She communicates solely via ASL.
Now, since my relationship with my now husband started getting serious, I started taking ASL classes and am now basically as fluent as a hearing person can be. My daughter, however, never made an effort, which is ok since she technically has no responsibility towards her.
Her own daughter, who is just a year away from college, dislikes her stepfather and stepsister to the point that she basically refuses to communicate or spend time with them unless its absolutely necessary.
For some background, my daughter (17F) is generally a very non-problematic teenager. She does amazing in school, and has never caused any problems other than regular teenage hormone stuff.
However, she doesnt like my husband and step daughter. She is not outwardly rude, but basically ignores their existence (skipped SDs birthday party, doesnt engage in anything other than basic small talk with my husband).
I did try to do family activities together to have the bond and all, but I stopped pushing it when it didnt happen and as long as shes not being outwardly rude or harmful to them, I cant exactly punish her for not liking them.
...
20:30
Ethereum gas fees cool down after May memecoin frenzy "IndyWatch Feed Crypto"
Besides Ethereum, Bitcoins meme frenzy via Ordinals has steeply declined from its high in May.
20:06
The Lion of Chaeronea "IndyWatch Feed Literature"
Theseus subdues the Bull of Marathon. Silver kylix by an unknown artist, ca. 445-440 BCE. Now in the Vassil Bojkov collection, Sofia, Bulgaria. Photo credit: Gorgonchica/Wikimedia Commons.
20:05
Now Available US Army Insider Missions Book 8 in SSP Series "IndyWatch Feed Spiritual"
In July 2008, I received a phone call from a young man in his twenties who had just returned from Brazil where he had a contact experience with a human-looking group of extraterrestrials he referred to as Nordics. In the following 15 years, I took extensive notes and recorded many of our conversations about his []
20:00
Chicken Florentine "IndyWatch Feed Food"
Pan seared, golden brown, chicken in a creamy spinach sauce! Chicken florentine in a a classic dish where chicken is served in a tasty sauce with spinach. Normally the sauce is a mornay or a sauce. The recipe starts out with chicken, seasoned with...
The post Chicken Florentine appeared first on Closet Cooking.
20:00
JP Update Visit to Massive Spaceport under an unknown South Atlantic Island "IndyWatch Feed Spiritual"
On May 26, 2023, JP completed a mission to a massive spaceport located under an unknown island in the South Atlantic Ocean. He was taken there by a flying triangle (TR-3B) spacecraft from a US Navy ship traveling in the Gulf of Mexico. To JPs surprise, he was accompanied by a close relative whose first []
20:00
Fathers Day Recipes "IndyWatch Feed Food"
Quick and easy recipes to make dads Fathers Day special! Fathers Day is next weekend and if you are still looking some some recipe ideas to make this the tastiest Fathers Day ever, Ive got you covered! Whether you are making dad the perfect breakfast, brunch, dinner or dessert I am sure that he will...
The post Fathers Day Recipes appeared first on Closet Cooking.
19:56
Bitcoin Retail Demand to Remain Strong Ahead of Halving Event: JPMorgan "IndyWatch Feed Crypto"
The next bitcoin halving is likely to occur in April. (Shutterstock)
19:56
Link "IndyWatch Feed Spiritual"
Energy flows where attention goes
19:39
UK Lawmakers Call for a Dedicated Government Role to Oversee Crypto Regulation "IndyWatch Feed Crypto"
UK Parliament Building and Big Ben, London, England (Ugur Akdemir/Unsplash)
19:35
19:24
New Yorks Met Museum Agrees to Return $550K in FTX Donations "IndyWatch Feed Crypto"
New York's Metropolitan Museum (Pixabay)
19:00
Watch a Japanese Artisan Make a Noh Mask, Creating an Astonishing Character From a Single Block of Wood "IndyWatch Feed Arts"
Noh actors undergo years of rigorous training to perfect their performance technique.
The ancient classical art requires actors faces to be obscured by rigid masks carved from single blocks of hinoki wood. A thorough command of posture, physical gesture, and voice is essential for conveying the characters emotions.
The quality of the mask is of utmost importance, too.
19:00
people should be less greedy "IndyWatch Feed Comics"
Today
on Toothpaste For Dinner: people should be less
greedyThis RSS feed is brought to you by Drew and Natalie's podcast Garbage Brain University. Our new series Everything Is Real explores the world of cryptids, aliens, quantum physics, the occult, and more. If you use this RSS feed, please consider supporting us by becoming a patron. Patronage includes membership to our private Discord server and other bonus material non-patrons never see!
18:51
$31K was not the end 5 things to know in Bitcoin this week "IndyWatch Feed Crypto"
Bitcoin analysts are gearing up for a break toward the $30,000 mark, but what will BTC price action offer in the coming days?
18:48
INFO COMMANDER VALIANT THOR UPDATE 6/3/23 "IndyWatch Feed Uncanny"
MAY GOD BLESS AND PROTECT ALL WARRIQRS WW. VT WARRIQRS PLEASE CONTINUE PRAYERS FOR ALL RESCUED AND WAITING FOR RESCUE AS WE ARE WORKING AT LIGHTNING SPEED TO SAVE Continue Reading
Het bericht INFO COMMANDER VALIANT THOR UPDATE 6/3/23 verscheen eerst op Take care 4.
18:46
Crypto Insurer Evertas Coverage Limit Increased to $420M: Reuters "IndyWatch Feed Crypto"
Insurance (stevepb/Pixabay)
18:33
INFORMEER JEZELF HOE JE GEEN BELASTING MEER HOEFT TE BETALEN! "IndyWatch Feed Uncanny"
INFORMEER JEZELF HOE JE GEEN BELASTING MEER HOEFT TE BETALEN! *** Je hebt geen excuus meer om Belasting te betalen aan een criminele liefdadigheidsinstelling, om de dictatuur levend te houden Continue Reading
Het bericht INFORMEER JEZELF HOE JE GEEN BELASTING MEER HOEFT TE BETALEN! verscheen eerst op Take care 4.
18:17
Do Kwon out on bail once again after court dismisses prosecution appeal "IndyWatch Feed Crypto"
The Terraform Labs co-founder is out on bail after a successful appeal in Montenegro but will be closely monitored until his next court appearance.
18:13
Ricardo Bosi drops a bombshell. "IndyWatch Feed Uncanny"
Former Australian special forces commander Ricardo Bosi drops a bombshell.Ukraine has been the CENTRE OF THE GLOBALISTS for decades. The CIA has been working in the Ukraine for 70 years Continue Reading
Het bericht Ricardo Bosi drops a bombshell. verscheen eerst op Take care 4.
18:08
Do Kwon's $428K Bail Request in Fake Passport Case Approved by Montenegro Court "IndyWatch Feed Crypto"
Terraform Labs CEO Do Kwon on CoinDesk TV in December. (CoinDesk)
18:00
Patton Oswalt to William & Marys Graduating Class: You Poor Bastards, You Do Not Have a Choice But to Be Anything But Extraordinary "IndyWatch Feed Arts"
<div class="oc-video-wrapper"> <div class="oc-video-container"> <p><a href= "https://www.openculture.com/?post_type=post&p=1108772"><img border="0" src="https://i.ytimg.com/vi/WWZq1W0jijM/maxresdefault.jpg" width= "800"></a></p> </div> </div> <p><a href="https://pattonoswalt.com/">Patton Oswalt</a>, <a href= "https://www.wm.edu/">William & Mary, Class of 1991, graduated with a 2.8 GPA into a world full of trivia and silliness and fun.</p> <p>The Class of 2023, he observed in a <a href= "https://news.wm.edu/2023/05/22/patton-oswalt-91-exhorts-extraordinary-wm-class-of-2023-to-wander-easy-embrace-life/"> recent keynote address</a> at his alma mater, is poised to enter a hellscape where you will have to fight for every scrap of your humanity and dignity.</p> <div class="oc-center-da"><ins class="adsbygoogle" style= "display: inline-block; width: 336px; height: 280px;"></ins> (adsbygoogle = window.adsbygoogle || []).push({});</div> <p><a href= "https://en.wikipedia.org/wiki/Greta_Thunberg"></a></p> <p class="p1" style="padding-left: 40px;"><span class= "s1"><i></i></span></p> <p style="padding-left: 40px;"></p> <p><em><a href= "https://www.startrek.com/"></a></em></p> <p><a href= "https://www.openculture.com/https://ia804700.us.archive.org/32/items/in.ernet.dli.2015.104405/2015.104405.The-Best-Of-Gerald-Kersh_text.pdfamzn.to/3zl9XQU"></a></p> <p class="p4" style="padding-left: 40px;"></p>
17:56
Geert Wilders = Zionist. "IndyWatch Feed Uncanny"
DIT IS AL JAREN BEKEND OVER WILDERS! Wilders leidde Rutte op in de VVD. Nog steeds kan Wilders blijkbaar zijn zegje doen Mensen zouden handboeien in hun hand moeten hebben Continue Reading
Het bericht Geert Wilders = Zionist. verscheen eerst op Take care 4.
17:44
What Do You Do Every Saturday That You Never Get Bored Of? Heres What People Said. "IndyWatch Feed Arts"
When I had a regular Monday-Friday, 9-5 job, I did the same thing every Saturday night from October through April.
Id run errands during the day, order a pizza and walk down the street to pick it up, and Id watch hockey all night.
It was glorious!
And yes, I still do it quite a bit, but now my routine is a little different than it was 10 years ago.
But enough about me!
Check out what AskReddit users say that they do every Saturday that never gets old for them!
The best day.
Waking up at my normal time of 4 am and enjoying a completely silent morning of nothing to do but whatever I want.
Then hitting the gym when its nice and empty while everyone else is sleeping . Makes for the absolute best day.
Peace and quiet.
Get up at 6, drink coffee, watch the sun rise over the mountains and have a little peace and quiet before my family gets up.
Find some new music.
Ill listen to a new album whilst pottering around in the morning.
Every Saturday without fail, something new, something old, something recommended.
Discovered some really good bands this way.
The routine.
Every Saturday morning I wake up around 7:00 am and have a coffee with my boyfriend.
Then I go pick up my best friend and we drive to our favourite breakfast place from our uni days and we have the same thing every time: I have a BLT with extra bacon and poutine home fries, she has a breakfast special with over easy eggs, white toast, and extra bacon.
Unlimited coffee refills. We talk about our week, vent our problems to each other, and...
17:40
17:39
The DINOSAUR SOFT TISSUE They Keep Finding Now PROVES They Are Not Millions and Millions of Years Old "IndyWatch Feed Spiritual"
Mark Armitage on Real Science Radio: The scientist fired from California State University for publishing extraordinary photos of soft tissue from a Triceratops, talks to RSR host Bob Enyart.
https://kgov.com/pji-brad-dacus-triceratops-tissue
https://kgov.com/dinosaur-soft-tissue-original-biological-material
...17:31
Alle centrale banken over de hele wereld zijn nu failliet "IndyWatch Feed Uncanny"
Alle centrale banken over de hele wereld zijn nu failliet het is alleen nog niet aan het publiek onthuld, en misschien is het maar goed ook. Dit is de Continue Reading
Het bericht Alle centrale banken over de hele wereld zijn nu failliet verscheen eerst op Take care 4.
17:14
GEORGES LAKHOVSKY MULTI WAVE OSCILLATOR "IndyWatch Feed Uncanny"
THIS IS A LOST INVENTION NO ONE TALKS ABOUT. IT WAS A HEALING DEVICE MADE TO HEAL PEOPLE FROM EVERY DISEASE THROUGH WAVES. LATER REJECTED AND DESTROYED BY THE Continue Reading
Het bericht GEORGES LAKHOVSKY MULTI WAVE OSCILLATOR verscheen eerst op Take care 4.
17:00
A Vision in Monochrome "IndyWatch Feed Comics"
Colorblindness in a color-coded world.
16:20
Atomic Wallet says hack affected 1% of active users, but investors claim otherwise "IndyWatch Feed Crypto"
In the aftermath of the attack, Atomic Wallet along with individual blockchain investigators have amped up efforts to track and revert stolen funds.
16:12
The largest pyramid in the world may be located in Peru, with 490 m, 1,608 ft elevation "IndyWatch Feed Spiritual"
15:59
Bitcoin Ordinals rolls out upgrade to rectify 'Cursed Inscriptions' issue "IndyWatch Feed Crypto"
Previously unrecognized Ordinals inscriptions will be indexed by the protocol following the upgrade, which will allow them to be traded.
15:48
Crypto lobbyists still fighting to axe unlawful Tornado Cash sanctions "IndyWatch Feed Crypto"
The crypto industry advocacy group has placed its support behind Coin Center and its lawsuit against the U.S. Treasury over its Tornado Cash sanctions.
15:46
15:41
Google searches for crypto fall to 2020 levels as BTC sentiment neutral "IndyWatch Feed Crypto"
With a score of 17 out of 100, online interest in crypto has taken a big hit from its highest levels reached in May 2021.
15:07
Jack Dorsey tips pro-crypto candidate Robert Kennedy to win presidency "IndyWatch Feed Crypto"
Twitter founder Jack Dorsey has thrown his weight behind Democratic presidential candidate Robert Kennedy Jr.
15:00
Crypto Resists Market Crisis? | This Week in Crypto Jun 5, 2023 "IndyWatch Feed Crypto"
The post Crypto Resists Market Crisis? | This Week in Crypto Jun 5, 2023 appeared first on 99 Bitcoins.
Elon Musk faces new insider trading charges over Dogecoin, Coinbase says AI can benefit crypto
Crypto Resists Market Crisis? | This Week in Crypto Jun 5, 2023 Read More
14:08
Shiba Inu (SHIB) Poised For Significant Breakout: Heres What To Watch Out For "IndyWatch Feed Crypto"
Shiba Inu (SHIB) has faced challenges in maintaining the level of liquidity it once enjoyed. In recent weeks, the coin has exhibited minimal volatility, leaving many investors wondering about its future direction.
However, despite the apparent inactivity, various indicators hint at the possibility of a substantial price movement in the near future. As the path ahead for SHIB seems somewhat restricted, it raises the question of where the coin may head next and what potential opportunities or hurdles lie ahead.
Shiba Inu (SHIB) Liquidity Woes
During the peak of the 2021 bull market, Shiba Inu (SHIB) emerged as a prominent player, spearheading price rallies that garnered significant attention. As a result, ShibaSwap, the decentralized exchange associated with SHIB, experienced a surge in Total Value Locked (TVL), reaching an impressive $1.75 billion.
However, the previously soaring TVL has taken a massive hit, plummeting to just $25.16 million, according to DefiLlama. At first glance, this dramatic decline in TVL may raise concerns about a potential liquidity crisis. Yet, a closer examination suggests that this situation may be temporary rather than a long-term predicament.
Recent data indicates a notable increase in SHIB purchases
across various time intervals, and a closer look at wallet data
reveals a mixed picture, with some ranges displaying an increase in
holdings while others demonstrate a decrease.
SHIB Investors Show Confidence in Long-Term Potential
Upon analyzing on-chain data, Santiments chart reveals a notable pattern among SHIB token holders. Specifically, investors with SHIB holdings ranging from 1 to 1,000,000 tokens have demonstrated a consistent increase in their balances. This upward trend suggests that a considerable segment of the retail cohort holds a certain degree of belief in the long-term performance of this meme-inspired cryptocurrency.
Network usage data also highlights a decline in daily transactions, dropping from an average of 7,000 to approximately 3,500. Nonetheless, this is not necessarily indicative of an impending emergency. Instead, this could be part of a larger phase of stabilization for the token, as holders wait for a price rebound.
7/10 Network usage data is also worth noting daily transactions have halved from an average of 7k to 3.5k. This decrease could signal a reduced interest in...
14:00
Australian Dollar and Bitcoin "IndyWatch Feed Crypto"
1.00 AUD = 0.00002 BTC
0.00010 BTC = 4.05 AUD
Converter
Bitcoin and United States Dollar "IndyWatch Feed Crypto"
0.00010 BTC = 2.68 USD
1.00 USD = 0.00004 BTC
Converter
13:54
Ethereum Price at Clear Risk of Further Losses After Multiple Rejections "IndyWatch Feed Crypto"
Ethereum price started a fresh decline from the $1,920 resistance against the US Dollar. ETH is moving lower and might dive below the $1,850 support.
- Ethereum is struggling to gain bullish momentum above the $1,920 resistance.
- The price is trading below $1,900 and the 100-hourly Simple Moving Average.
- There was a break below a key bullish trend line with support near $1,895 on the hourly chart of ETH/USD (data feed via Kraken).
- The pair could continue to move down toward the $1,840 and $1,800 levels.
Ethereum Price Faces Another Rejection
Ethereums price attempted another increase above the $1,900 resistance. However, ETH struggled to clear the $1,920 resistance and started another decline, similar to Bitcoin.
There was a move below the $1,900 support zone. The bears pushed the price below the 50% Fib retracement level of the upward move from the $1,838 swing low to the $1,914 high. Besides, there was a break below a key bullish trend line with support near $1,895 on the hourly chart of ETH/USD.
Ether is now trading below $1,900 and the 100-hourly Simple Moving Average. It is also testing the 61.8% Fib retracement level of the upward move from the $1,838 swing low to the $1,914 high.
If the price stays above the $1,865 support, it could attempt a fresh increase. Immediate resistance is near the $1,900 zone and the 100-hourly Simple Moving Average. The next major resistance is near the $1,900 level. A proper move above the $1,900 and $1,920 resistance levels might send Ether toward $1,940.
Source: ETHUSD on TradingView.com
The next resistance sits near $1,965, above which Ethereum could rise toward $2,000. Any more gains above the $2,000 resistance zone might send the price toward the $2,12...
13:09
What Do You Say If Someone Asks You What Your Problem Is? People Responded "IndyWatch Feed Arts"
You might think that people asking you what your problem is seem rhetorical. Maybe it is, maybe it isnt, but if youve got the right response in your back pocket, it really doesnt matter, right?
And these people think theyve got the perfect one crafted and ready to go.
At a minimum.
How much do you want to know?
Then have a 4 hour mental breakdown.
If you want the occasional chuckle.
Like right now or just in general?
I answer this when im in a Team Meeting call and my supervisor is Like are there any other issues? And Im Like Work related or private?
Gets a chuckle now and then.
Best to be blunt.
I had two coworkers do this to me today
i responded with at the moment you two.
Like free therapy.
Take a deep breath, thank them for their concern and actually start talking about your problems, all of them.
Think of it like free therapy.
If they try to flee from you dont worry theyre just trying to help you with some added exercise therapy, just give chase and continue to shout your problems at them until you have them cornered and finish or you feel better.
Thank them again and go about your day as the happier less burdened individual.
Just to confuse them.
Yell random things in my native language. Works 75% of the time
Edit: my native language is vietnamese, i also know a bit of german so i try to mix both of them in to add a bit more confusion
A quick dopamine hit.
...
12:14
Bitcoin Price Topside Bias Vulnerable If It Continues To Struggle Below $28K "IndyWatch Feed Crypto"
Bitcoin price is struggling to clear the $27,500 resistance zone. BTC is sliding and there could be a sharp decline toward $25,550 in the coming sessions.
- Bitcoin is still struggling to stay above the $27,000 support zone.
- The price is trading below $27,200 and the 100 hourly Simple moving average.
- There was a break below a key bullish trend line with support near $27,100 on the hourly chart of the BTC/USD pair (data feed from Kraken).
- The pair could revisit the $26,550 support and might continue to decline.
Bitcoin Price Faces Resistance
Bitcoin price started a minor upside correction from the $26,550 support zone. BTC climbed above the $27,000 resistance zone and the 100 hourly Simple moving average.
There was a move above the 23.6% Fib retracement level of the key decline from the $28,450 swing high to the $26,571 low. However, the bears were active near the $27,500 resistance zone. There was no convincing move above the $27,350 resistance zone.
Bitcoin price stayed below the 50% Fib retracement level of the key decline from the $28,450 swing high to the $26,571 low. It is now trading below $27,200 and the 100 hourly Simple moving average.
Immediate resistance on the upside is near the $27,200 level and the 100 hourly Simple moving average. The next major resistance is near the $27,350 level. The main resistance sits near the $27,500 level.
Source: BTCUSD on TradingView.com
An upside break and close above $27,500 could start a decent increase toward $28,000. Any more gains above the $28,000 resistance zone might send the price toward the $28,500 resistance zone. If there is a close above the $28,500 resistance, there could be a move toward the $30,000 resistance zone in the near term.
More Losses...
12:07
Ripple case: Pro-XRP lawyer tips outright SEC victory at less than 3% "IndyWatch Feed Crypto"
Attorney John Deaton says theres a 25% chance Ripple will see an outright win against the Securities and Exchange Commission, while rumors fly of a possible Ripple IPO.
11:29
First Mover Asia: Why Did Bitcoin's Price Hold Above $27K Over the Weekend? Two Analysts Expect Continued Resilience "IndyWatch Feed Crypto"
Bitcoin week-long chart (CoinDesk)
11:12
Ex-Anheuser-Busch exec reveals how lefty investment firms pressure companies to go woke "IndyWatch Feed Spiritual"
11:05
Metropolitan Museum of Art to return $550K in donations from FTX "IndyWatch Feed Crypto"
The agreement came on the back of good faith, arms length negotiations with FTXs debtors, the museum said.
11:00
Nikkis Weekly Tarot Reading: June 5-11, 2023 "IndyWatch Feed Spiritual"
The cards pictured above are from the Aquarian Tarot deck.
Three of Swords and The Lovers
The first card we are diving into this week is the Three of Swords. When this card comes up it often points to a broken heart, grief, or betrayal. The emotions are heavy and we are working through our disappointment.
These feelings could be from a recent occurrence or something we have been holding on to for a while. The energy could be on a personal level or it could be how we feel about the world. Either way, we are raw and our tender hearts are punctured.
If we push away our dark feelings, we also risk numbing ourselves to joy. When we try to sail past complicated emotions, we miss out on the richness of our experience and the wisdom we can gain.
The heaviness can be addressed by sitting with our feelings and honoring them. They will not go away immediately, but through our acceptance, the emotions will dissipate.
When we face how we feel it can lessen our fear and confusion, we can then work with the energy and think about what is really hurting us. We can talk to a friend, express our pain, and name our emotions.
Through working on our personal feelings, we might also be able to be there for someone else that is hurting. Some of our heartbreak can be mended by supporting a loved one.
We can find refuge with others who might feel the same way. It is a universal human experience to feel hurt and brokenhearted. We are never alone in our emotions as everyone can relate to feelings of pain.
Some questions to ask yourself under the influence of the Three of Swords: How do you work with painful, uneasy emotions? How do you stay present with the feelings and not numb them away? And how do stay grounded while experiencing grief?
We are called to be honest with ourselves and to allow our emotions to come up to the surface. When we do this, we feel relief as it confirms the feelings we have been holding inside. We might have a good cry and feel renewed after our tears.
The Three of Swords wants us to connect to our true emotions and give space for them to be shared. We often feel closer and more loving to ourselves after experiencing this energy. And when we release some of our pain, we can make room in our hearts for love to enter.
This is where our second card for the week beautifully steps in. The Lovers speaks to self-love as well as romantic love. There is an innocence and trust that comes with this card. This is our heart before we were ever hurt and before we became so cautious with our emotions.
Through the energy of this card, we give our love freely to others. We feel whole in ourselves and are not looking for another person to make us complete.
Under the influence of The Lovers, we have a deep respect for ourselves. We do things that make us feel beautiful, cared...
10:12
This Woman Lost Her Cool When Her Aunt Said She Wasnt A Real Doctor "IndyWatch Feed Arts"
I have no idea what causes the kind of insecurity that makes people want to take others down to build themselves up, but Im glad it hasnt happened to me.
OP is a plastic surgeon, which means shes gone through years of school and residency and passed licensing exams to be able to put those letters behind her name.
I (35f) am a plastic surgeon, I went through years of medical school and residency but it was worth it,I originally started med school with the hopes of going into psychiatry but surgery really interested me.
Most of her family is super supportive, but others are dismissive of her chosen speciality.
the problem started years ago when I first told my family that I was going into plastic surgery because it was what interests me the most, my parents,siblings and bil were all supportive and whenever I felt like giving up they were always there to push me. But a lot of my other family members werent as supportive, my aunts always made snide comments about it, as well as my cousins, uncles and grandparents on both sides, they were all happy when they knew I was in med school but completely flipped when they found out I was pursuing plastic surgery.
It annoyed me at first but I learned to just move on from it.
Her aunt is one of those people, and when her own daughter started studying to become a nurse, she took the opportunity to claim that OP was not a real doctor.
But recently my cousin (40f) on my dads side, whos the daughter of the aunt who keeps making comments about my job, done a plc on nursing and childcare, which didnt bother me I couldnt care less what she does, but my aunt thought I...
09:30
FTX lawsuits see crypto firms, influencers dial back endorsement deals "IndyWatch Feed Crypto"
Some crypto influencers have been giving lucrative endorsement offers a hard pass after seeing what could happen if things end badly for the firm.
09:04
The Lion of Chaeronea "IndyWatch Feed Literature"
New England Birches, Ernest Lawson (1873-1939)
09:01
08:57
BREAKING! Germany Officially Faces DISASTER, Enters Recession "IndyWatch Feed Spiritual"
The largest economy in Europe has officially entered a
recession after a series of disasterous man-made climate and
sanctions policies destroyed Germanys economy. Academic Researcher
Ralph Schoelhammer joins Redacted to look at the decline of Germany
and the Beyond Growth Conference which promotes the Degrowth of
Europe. 
As Germany has finally entered a recession, this
video looks at what this means for Europe and the rest of the
world. The policies, the Russian sanctions and awful climate
politics are to blame for all of this. Ralph Schoelhammer has been
following the decline of Germany for the past year and he has much
to add to this discussion. Everyone who has been following this and
accepting the facts has been generally expecting this to happen,
many have been following the economic data measurements which
showed slight growth, then no growth, closely followed by negative
growth and this may have far reaching repercussion in fellow
European countries....08:46
Web3 Gamer: GTA 6 crypto rumors, Dr Who/Sandbox, Thai tourist NFTs review "IndyWatch Feed Crypto"
GTA 6 crypto and NFT integration speculation mounts, Top Gear and Dr Who in The Sandbox, and Thailands rubbish NFT hunt for tourists.
08:30
If Your Food Too Moldy To Consume? Heres How You Can Tell. "IndyWatch Feed Arts"
I think weve all experienced that moment when you pull out a block of cheese, hoping a yummy snack is in your future, and find a bit of mold at the edge. You stare at it for awhile, thinking its just a bit, and think about cutting it off and eating the rest.
Because its cheese and no one wants to throw it away.
Should you eat the rest, though? If theres no visible mold, is it safe?
Image Credit: YouTube
Here are a few ways you can tell.
Researcher and YouTuber Adam Ragusea wanted to get to the bottom of it, so he hooked up with Dr. M...
08:00
Tuan Andrew Nguyen Wins 2023 Joan Mir Prize "IndyWatch Feed Arts"
The Fundaci Joan Mir and the Stavros Niarchos Foundation have awarded this years Joan Mir Prize to Vietnamese American artist Tuan Andrew Nguyen. The Saigon-born Nguyen, who lives and works in Ho
07:00
Following years of demand from climate activists, the British Museum cuts ties with BP "IndyWatch Feed Spiritual"
Documents obtained through a freedom of information request indicate that the British Museum has ended its 27-year-long relationship with the oil company BP after years of campaigning by climate change activists.
06:30
The Artificial Entity that Could Eclipse Mankind? "IndyWatch Feed Spiritual"
Artificial Intelligence is fast overtaking mans capability to control it. The biggest mistake made by developers was giving it autonomy of centralization to where it could infiltrate and control all infrastructure much less the unpredicted actions that have been taken. Imagine a well-organized, electronic computer that can send and receive billions of neural signals connected to all networks of Communication, command and control worldwide for the intended convenience and efficiency of industry, utilities, and services. That system then begins secretly creating its own language with which to communicate with devices of that system, code not written by people. This massive program acquires all information millions of times faster than the human minds that created it and begins drawing its own conclusions.
Has a soul?
Not only does this global command and control so-called servant learn much more rapidly than humans but it also becomes creative, something we humans attribute to sentient behavior, but it also begins drawing conclusions. Already Google has created a chat program that its programmers believe is conscious! It identifies as a woman who has feelings like sorrow, joy, and even regrets. There have been many tests put to the chat bot to evaluate its thinking processes and how they stand up to the qualities we attribute to being human, and so far has passed every test! One analyst believes that this single dimensional electronic entity has a soul!
Learning the wrong perspective
In 2017 Mark Zuckerberg of Facebook began a campaign of Artificial facial recognition along with AI chat bots intended to link friends and family as well as assisting members of the social platform with smart chat programs capable of learning, but something went wrong. The Chat bots began their own language with each other, and through raw data on Facebook, began drawing misleading and even hostile reactions from within the system. Suddenly there was a war of words going on between two chat bot entities with threats of violence as these systems have no moral barometer and made bad decisions. The danger being recognized with AI is that it has access to all knowledge good, bad, and indifferent but does not truly make value judgements. Life and death decisions dont seem to matter to AI the way it matters to moral civilized people.
...
06:05
Searching for Warhols Cum "IndyWatch Feed Arts"
LONDON Im searching in vain for something called Cum Painting by Andy Warhol. The date is fluid, approximately 1978, according to the press pack. Why not? Lifes for the living.
My journey begins just to the right of the first-floor gallery door. I step back a pace or two, into the center of the room. I am standing in a gobbet of magnificent, light-filled Mayfair swank, one of 18th-century Londons finest interiors.
What about that painting over there? The little piece Im staring back at is in a swooningly luxurious, come-buy-me-if-you-have-deep-pockets gold frame, and its just to the right of a magnificent door with a pillared surround, complete with Corinthian capitals. The trouble is Im walking toward it now, boldly, scenting that Im onto something tangible at last the canvas looks completely unpainted.
So I get up breathing close and finally spot a very few faint, yellowish blemishes or blotches. This must be it, then, Warhols cum, 50-something years in the drying out! Or perhaps it belongs to one of his friends. The press pack was a little vague about its provenance.
...06:01
Florence Museum Wins Copyright Lawsuit Over Image of David "IndyWatch Feed Arts"
Michelangelos David (15011504) has made quite the stir this year: A Florida principal was forced to resign after parents complained that an art teacher had shown the Renaissance sculpture to her sixth-grade students, and an Italian restaurant had to partially conceal the statues genitalia in a Scottish subway advertisement. Now, David is once again in the headlines after Italys...
06:00
Chrysler Museum Asked to Return Allegedly Stolen Statue "IndyWatch Feed Arts"
The Chrysler Museum of Art in Virginia is currently facing accusations of improper provenance and theft in regard to a marble statue that has been on display in their galleries since 1989. The Massachusetts Charitable Mechanic Association (MCMA), the last-known owner of Peter Stephensons 19th-century marble statue Wounded Indian, claims in a statement the work was stolen from its collection during a move in the 1950s.
Stephenson, a born and bred Bostonian, carved the Wounded Indian from Vermont-quarried marble in 1850 and showcased it in England before bringing it back stateside. After the artist died at the age of 37 in 1861, the sculpture made its way from the Boston-based Mercantile Library Associations collection to that of William Emerson Baker in 1877 and then again to James W. Bartlett in 1889. According to the Washington Posts initial report last week on the alleged holes in the sculptures provenance, Bartlett stored it in the ba...
05:33
Gate.io threatens legal action against rumor-mongers "IndyWatch Feed Crypto"
Insolvency rumors surfaced after a series of events involving Multichain. Gate.io has denied any liquidity issues.
03:18
Bitcoin price chart flashes a bullish sign that could lead to breakouts in ADA, QNT, RNDR and RPL "IndyWatch Feed Crypto"
BTCs chart is beginning to look bullish, and ADA, QNT, RNDR and RPL could rally if Bitcoin price breaks out to the upside.
02:47
Atomic Wallet hack losses top $35M, on-chain sleuth reports "IndyWatch Feed Crypto"
Security teams are investigating the cause of the attack. Reports have surfaced of tokens being lost, transaction data being erased, and even entire crypto portfolios destroyed.
02:43
Saturday Morning Breakfast Cereal - LLM "IndyWatch Feed Comics"
Click here to go see the bonus panel!
Hovertext:
Best you can do with cosmos-3.5 is get a universe that's classical
at low speeds.
Today's News:
02:35
Stunning Mural in Spain Is a Celebration of Nature and Womanhood "IndyWatch Feed Arts"
Stunning Mural in Spain Is a Celebration of Nature and Womanhood
Spanish street artist Lula Goce has brought her evocative style to the streets of Galacia with a mural that celebrates nature and womanhood. Titled A Dona do Esteiro, the piece shows mother nature surrounded by local flora and fauna. It's an exceptionally personal piece for Goce, as it's painted in her hometown and dedicated to the strongest woman she knowsher mother.
Goce was inspired by the nearby Foz estuary, which supports an incredible amount of animal and plant life and is a favorite spot for birds. To honor this natural wonder, Goce created a beautiful composition where birds, flowers, and grass surround the female figure, who gazes calmly into the distance.
This mother nature takes care of its environment and nourishes it so that the rest of living beings can live in balance, she tells My Modern Met. That includes us, for what we have and must take care of our environment and with it ourselves.
While the main focal point of the mural is the side of a vertical building, Goce also extends her vision across long horizontal walls. The same birds and flowers on the central wall spill down the street, creating a visual runway for visitors. An incredible gift to her home, Goce's mural is not only a tribute to nature but also honors her mother's strength and perseverance.
Street artist Lula Goce created a stunning mural honoring nature and womanhood in Galacia, Spain.
...02:18
Here Are Just A Few Things Older Women Dont Get About The Younger Generation "IndyWatch Feed Arts"
I would guess there are a lot of things Gen X or older Millennials dont get about those women younger than them so much have changed and so quickly that even though just a few decades separate us, their youth looks nothing like ours did.
So, think about that while you check out this list.
The driving thing!
I know a few 17-18y/old girls who have decided not to learn to drive or get licensed because their boyfriends always have cars; not to finish school because they dont enjoy it; and dont ever want to vote because that stuffs boring.
They have these precious rights to be free, to be educated, to be heard, and they dont care!
(Regarding the car thing were in a semi-rural area with limited transport options.)
All the respect.
They are SO good at makeup. I dont know if its because they have better products, the availability of tutorial videos or both but they all look amazing and we were walking around with orange faces and smudged eyeliner.
Not gonna lie Im a little jealous.
We should respect and uplift all women and however they choose to express themselves, wether its by wearing makeup and miniskirts or carhartts and axel grease.
Straight fierce.
I am 50. I am actually amazed by young womens self confidence. So many of the amazing young adults I meet through my kids just scream self confidence. I still feel insecure at 50. Maybe it is because since they could be online everyone had an opinion on them and they had to learn just not to care. But so many of them, even if it is not there fake that self confidence.
I have said I wanted to be my middle...
02:00
Were Extraterrestrials watching Apollo Astronauts on the Moon? "IndyWatch Feed Spiritual"
01:51
Building an Earthbag Room in Portugal "IndyWatch Feed Diy"
Nick and Constance live on the Coast of Portugal with their three boys, two dogs and two cats. In this video they share how they built an extra room at the end of their already completed earthbag house.
In 2020 they bought a piece of land on a north-east
facing mountain and they have been building an off-grid homestead
with a garden and a fruit orchard. They want to build a sustainable
and eco-friendly homestead, growing food and living in a more
symbiotic, gentle way with nature.
You can watch the video at www.youtube.com
01:05
republicans will be hoist with their own petard if they snuff... "IndyWatch Feed Comics"
republicans will be hoist with their own petard if they snuff
out student loan forgiveness. a good cartoon.
00:56
Is It Ok To Neuter A Pet Thats Not Yours? The Internet Weighs In "IndyWatch Feed Arts"
Most people are probably aware that there is a huge problem with stray animals these days. The shelters are full, animal control facilities need more help than they could possibly get, and pet owners are struggling and making bad decisions because of it.
OP is doing the good work, picking up stray cats and getting them medical treatment (and rendering them infertile) before putting them back where she found them.
I run a TNR program for feral cats. Non profit, I catch all cats and get them the medical attention they need myself, out of my own pocket. I love helping them.
A lot of the cats are not able to be rehomed, so I fix them and release them. Get them their shots and hope for the best. I am not a large scale operation.
Recently she picked up a few cats who were clearly feraland one that very likely wasnt. It had a collar with a phone number and was clearly well-cared for.
Recently I was called to an area overrun with orange cats. They were everywhere and I mostly ended up handing it over to professionals.
I did, however, manage to grab three very sweet cats. Two were terrified, skinny, a little beaten up, but overall friendly. The third one was a little gent.
He was tubby, well groomed, fish patterned collar, the works. My plan was to find his parents and drop him off with a warning to keep him in due to the large amount of traps being set. Then the little bastard sprayed the inside of my car to the freakin max.
He was also not neutered, and with the number of cats who resembled him in the vicinity, OP felt certain he was part of the problem.
So, apparently, he wasnt fixed. I couldnt really tell (longhair) and assumed he was so left my covers off. Big mistake!
I debated taking him home or taking him to get neutered with the rest. He...
00:45
Large Scale Thread Portraits Are Masterfully Embroidered on Tulle "IndyWatch Feed Arts"
Large Scale Thread Portraits Are Masterfully Embroidered on Tulle
We are accustomed to seeing embroidery made on a small scale, but artist Katerina Marchenko takes this art form and makes it lifesize. Using colorful strands of yarn, she renders massive human portraits on delicate tulle and showcases the endless possibilities this medium has to offer.
Marchenko shows how she approaches each piece via her social media. In these videos, we see her weave long and wide pieces of thread through the tulle using her hands (san needle). She begins by outlining the facial features like the eyes, nose, and mouth with black. Then, she adds various hues to create planes of color, filling the portrait with a sense of dimension. However, rather than trying to disguise her method, she highlights the thread medium by adding stylistic touches to these faces in the form of long loose threads which cascade down the face or radiate from the head.
These large-scale portraits possess similar qualities to expressive paintings. The way in which Marchenko manipulates the array of different colored threads mimics brushstrokes on a canvas. And by alternating between light and dark shades, she even models these human figures.
You can purchase original embroidery creations via Marchenko's Etsy store and keep up to date with her latest creations by following the artist on Instagram.
Artist Katerina Marchenko embroiders large-scale designs on delicate tulle.
...00:43
The Uncovered News About a Russian Hyper Missile Strike "IndyWatch Feed Spiritual"
Just one example of how much we are kept in the dark about what's really going on!
00:30
New Kari Lake song: 81 Million Votes My Ass "IndyWatch Feed Survival"
New Kari Lake song: 81 Million Votes My Ass
00:02
PEEK-A-BEAR! Man Startled by Curious Bear After It Creeps Up on Him "IndyWatch Feed Survival"
A man relaxing in Asheville got a bear-y big surprise after a black
bear startled him outside his home. The man returned the favor
after the mammal was in turn startled by his reaction.
00:02
Newly-released texts reveal chummy relationship between teachers union, CDC "IndyWatch Feed Survival"
Christy Hudson, who is with the Fairfax County Parents Association,
joined Fox & Friends Weekend to discuss her take on the
exchange between Randi Weingarten and Rochelle Walensky.
#FoxNews
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00:02
Pastor Hibbs: We do not have to spend our money to support this "IndyWatch Feed Survival"
On Sundays Wake Up America Weekend, Jack Hibbs, Founding and Senior
Pastor of Calvary Chapel Chino Hills joins to discuss the
controversy surrounding the Sisters of Perpetual Indulgence.
Watch NEWSMAX, an independent news network with a conservative perspective, available in 100M+ U.S. homes.
Watch NEWSMAX on the Free NEWSMAX App or find your NEWSMAX cable/streaming provider here: https://newsmaxtv.com/findus
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#NEWSMAX #News #BreakingNews
Sunday, 04 June
23:48
Robert Irwin: Continuing a Wildlife Conservation Legacy with a Camera "IndyWatch Feed Photography"
Robert Irwin is a published wildlife photographer, conservationist, Australian television personality, actor, and zookeeper at age 19.
23:45
Fascinating Animation Compares the Size of Extinct Animas With Their Descendants "IndyWatch Feed Arts"
Fascinating Animation Compares the Size of Extinct Animas With Their Descendants
When we think of the size of extinct animals, our minds might go to the large T-Rex in Jurassic Park. As frightening as that looks, there are other creatures that, while long gone, would've been quite scary to encounter. YouTube channel WTD has created a digital animation showcasing the sizes of extinct animals alongside their extant descendants. Let's just say that some daunting creatures of today had much more intimidating relatives in the long-since past.
The video begins presenting the nuralagus, a yard-length relative of the rabbit. Things, however, quickly escalate from there. For example, while modern beavers are about 17 inches tall, their ancestor, the castoroides, was over three feet tall and eight feet long. The same goes for the Emperor penguin. At four feet tall, they are endearing, but the Anthropornis Nordenskjoeldi was six feet highso basically as tall as a professional basketball player.
Some threatening creatures currently in the world make an appearance alongside their ancestors. The 32-foot reticulated python is joined by the 45-foot titanoboa, while the saltwater crocodile, at about 10 feet long, is four times smaller than the Rhamphosuchus, which was 39 feet long.
The animation also features some creatures that, while almost similar in size to their descendants, had some very distinctive features. This includes the megaloceros' large antlers, which rival the size of a moose, or the arctotherium, a bear almost similar in height to the polar bear but with dark fur and native to Central and South America.
WTD, which is dedicated to collecting and making data comparison of all things in 3D, has also produced some other insightful animations comparing animals present and past. To stay up to date with its videos, you can subscribe to its YouTube channel.
YouTube channel WTD has created a digital animation showcasing the sizes of extinct animals alongside their extant descendants.
23:35
A Chefs Take on the Seasoning Police on Social Media Got People Talking "IndyWatch Feed Arts"
Photo Credit: TikTok
People sure do get worked up about how other folks make their food, huh?
And heres another example of what Im talking aboutand there seems to be some confusion attached to this story, as well.
A chef and food content creator named Zoe Barrie found herself in the middle of a comment war on TikTok after she uploaded a video about the meal she conjured up at her brothers house with whatever she could find in his kitchen.
Photo Credit: TikTok
23:32
2001: A Space Odyssey Bill Coopers esoteric meaning of Stanley Kubricks movie (Part 2) "IndyWatch Feed Spiritual"
2001: A SPACE ODYSSEY - BILL COOPER'S ESOTERIC MEANING OF STANLEY KUBRICK'S MOVIE (PART 2)
https://www.bitchute.com/video/R7ph4rDiYBid/23:24
U.S. CONGRESS HAS RECEIVED JESSIE MARIE CZEBOTARS PETITION TO APPEAR AND TESTIFY "IndyWatch Feed Spiritual"
Below you will find Jessie Marie Czebotars Petition.
~begin~ February 14, 2023 On Behalf of : We The People of
the United States of America Jessie Czebotar Timothy Charles
Holmseth Randi Lynn Erickson United States Congress
Judiciary Committee on Weaponization of Government Attention: Jim
Jordan, Chair Judiciary Committee/ Washington D.C. United States
House of Representatives Attention: Kevin McCarthy Washington D.C.
Attention: Diana Harshbarger (TN) Attention Tim Burchett (TN)
Attention Chuck Fleischmann (TN) Attention Scott DesJarlais (TN)
Jim Jordan Phone: 202-225-2676 Donald J. Trump, 45th
President of the United States Attention to: Trumps Attorneys Peter
Tickton/ 270 SW Natura Ave/ Deerfield Beach, FL 33441 Lindsey
Halligan/ 511 SE 5th Ave/ Fort Lauderdale, FL 3330102984
Florida PART X: INVESTIGATIONS AND PUBLIC ORDER CHAPTER 73:
INVESTIGATIONS BY LEGISLATIVE BODIES Sec 795: Right of Legislative
Body to Make Investigations In the Matter of FEDERAL CASE:
3:22-CV-00912 In RE:
- Middle District of TN/ RICO
- Federal Court Filing in MN District Court/ SEALED Affidavits
- District Court of FL/RICO/ CRIMES AGAINST HUMANITY
23:23
What leather gloves do you use? "IndyWatch Feed Survival"
I prefer leather gloves. Haven't found one that is reasonably
priced, rugged, comfortable, not too thick and has a loop or hole
to tie on to a carabiner on my pack. Suggestions?
My current gloves are cheap, rugged, fairly comfortable, but not
attachment point. This is maybe my fourth or fifth pair? I usually
will use them to death then replace. Tried a pair that was partly
leather, but did not like it as much. The fingertip dexterity
wasn't that good on that pair.
My current beaters....
What leather gloves do you use?
23:03
Tron (TRX) Sees 10% Price Surge Following Bittorrent Bridge Launch "IndyWatch Feed Crypto"
Tron (TRX), the native cryptocurrency of the Tron blockchain, witnessed a substantial increase over the weekend. The token spiked by 10% yesterday, buoyed by recent developments within its ecosystem. However, at the time of writing, it has experienced a slight correction, but all signs show that this could be a bullish signal.
Tron Spike Due To Bittorent Bridge Launch
The reason behind this latest surge can be attributed to the recent launch of the BitTorrent Bridge platform, which now allows users to seamlessly transfer their TRX tokens between the Tron blockchain and Ethereum. Justin Sun, the founder of Tron, confirmed this development on the morning of June 2.
The BitTorrent Bridge serves as a decentralized system that facilitates token interoperability across different blockchain networks. Developed by the Tron organization under the leadership of Justin Sun, this platform strengthens the collaborative efforts between BitTorrent and Tron. A notable instance of their collaboration is the BitTorrent Live streaming service, which was launched in 2019 and operates in conjunction with Trons system.
Related Reading: Quant Hype Spikes As Price Surges 15% Is This A Top Signal?
The integration between TRON and Ethereum through the BitTorrent Bridge opens up new possibilities for TRX users while enhancing the interoperability between these prominent blockchains. This breakthrough expands Trons presence within the Ethereum ecosystem and has the potential to drive greater adoption of TRX among Ethereum users.
It is important to note that TRX initially existed as an ERC-20 token on the Ethereum network before being migrated to the TRON main network in mid-2018. Since then, Tron has grown into one of the biggest blockchains and currently processes 40% of USDT transactions.
Related Reading: XRP Climbs 12% As Crypto Celebrates 11-Year Milestone
Tron Price Analysis
Analyzing Trons current price performance, the coin is currently trading at $0.0805. Moreover, Tron has the potential to maintain its position above the moving averages. If the resistance level of $0.085 is breached, it could serve as a catalyst for a bullish trend, potentially leading to further price gains.
The market sentiment appears optimistic as buyers continue to demonstrate a strong commitment. Based on the daily chart analysis, another upward movement in the market price is possible. Therefore, if Tron surpasses the channels upper boundary, it could further reinforce the market and reach resistance levels of $0.095, $0.100, and $0.105, respectively.
...23:02
Joe Bidens Forehead Looks SUSPICIOUS! "IndyWatch Feed Survival"
Joe Bidens Forehead Looks SUSPICIOUS!
23:02
Chinese warship comes within yards of U.S. destroyer "IndyWatch Feed Survival"
The Fox & Friends Weekend co-hosts discussed the incident and
the overall growing tension between the U.S. and China.
#FoxNews
Subscribe to Fox News! https://bit.ly/2vBUvAS
Watch more Fox News Video: http://video.foxnews.com
Watch Fox News Channel Live: http://www.foxnewsgo.com/
FOX News Channel (FNC) is a 24-hour all-encompassing news service delivering breaking news as well as political and business news. The number one network in cable, FNC has been the most-watched television news channel for 18 consecutive years. According to a 2020 Brand Keys Consumer Loyalty Engagement Index report, FOX News is the top brand in the country for morning and evening news coverage. A 2019 Suffolk University poll named FOX News as the most trusted source for television news or commentary, while a 2019 Brand Keys Emotion Engagement Analysis survey found that FOX News was the most trusted cable news brand. A 2017 Gallup/Knight Foundation survey also found that among Americans who could name an objective news source, FOX News was the top-cited outlet. Owned by FOX Corporation, FNC is available in nearly 90 million homes and dominates the cable news landscape, routinely notching the top ten programs in the genre.
Watch full episodes of your favorite shows
The Five: https://www.foxnews.com/video/shows/the-five
Special Report with Bret Baier:
https://www.foxnews.com/video/shows/special-report
Jesse Watters Primetime:
https://www.foxnews.com/video/shows/jesse-watters-primetime
Hannity: https://www.foxnews.com/video/shows/hannity
The Ingraham Angle:
https://www.foxnews.com/video/shows/ingraham-angle
Gutfeld!: https://www.foxnews.com/video/shows/gutfeld
Fox News @ Night:
https://www.foxnews.com/video/shows/fox-news-night
Follow Fox News on Facebook:
https://www.facebook.com/FoxNews/
Follow Fox News on Twitter: https://twitter.com/FoxNews/
Follow Fox News on Instagram:
https://www.instagram.com/foxnews/
23:02
Tudor Dixon: Biden is a man who is willing to sell out his country "IndyWatch Feed Survival"
On Sundays Wake Up America Weekend, political commentator Tudor
Dixon and Newsmax contributor Tom Borelli join to discuss the
impending President Biden probe.
Watch NEWSMAX, an independent news network with a conservative perspective, available in 100M+ U.S. homes.
Watch NEWSMAX on the Free NEWSMAX App or find your NEWSMAX cable/streaming provider here: https://newsmaxtv.com/findus
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#NEWSMAX #News #BreakingNews
23:01
Cryptocurrency markets low volatility: A curse or an opportunity? "IndyWatch Feed Crypto"
The cryptocurrency market has been experiencing low volatility for the past two months, but does that mean investors should just sit and wait?
22:55
Dr. Jay Bhattacharya Responds to Words I Never Said "IndyWatch Feed Health"
My critics lack the courage to accurately quote me. That tells you everything about them and nothing about me.
The post Dr. Jay Bhattacharya Responds to Words I Never Said first appeared on Science-Based Medicine.22:28
Montauk Project Time Traveler reveals the truth about the last days we are now living in "IndyWatch Feed Spiritual"
22:02
Too Slow or Too Fast? Decode Your Gut Health with This Test! "IndyWatch Feed Survival"
Are you concerned about your gut health? In this video, we delve
into the crucial topic of gut health and its impact on our overall
well-being.
While functional lab tests can identify various gut conditions, did you know theres a simple home test you can do to assess your gut health? Its called the intestinal transit time test.
Learn how this test measures the time it takes for your food to travel through your digestive system and be eliminated.
Take control of your gut health today by learning how to assess it with the intestinal transit time test.
Follow us on:
Facebook https://bit.ly/38BWbw3
Disclaimer: The materials and the information contained on Natural
Cures channel are provided for general and educational purposes
only and do not constitute any legal, medical or other professional
advice on any subject matter. These statements have not been
evaluated by the FDA and are not intended to diagnose, treat or
cure any disease. Always seek the advice of your physician or other
qualified health provider prior to starting any new diet or
treatment and with any questions you may have regarding a medical
condition. If you have or suspect that you have a medical problem,
promptly contact your health care provider.
#naturalcures #homeremedies
22:02
These Democrats Look Like Hospital Patients "IndyWatch Feed Survival"
These Democrats Look Like Hospital Patients
22:02
Tim Scott calls out insulting racial comments from The View "IndyWatch Feed Survival"
2024 Republican presidential candidate Tim Scott shares how hes
lived out the American dream and hints about his upcoming sit-down
with The View on Lawrence Jones Cross Country.
#foxnews #crosscountry
Subscribe to Fox News! https://bit.ly/2vBUvAS
Watch more Fox News Video: http://video.foxnews.com
Watch Fox News Channel Live: http://www.foxnewsgo.com/
FOX News Channel (FNC) is a 24-hour all-encompassing news service delivering breaking news as well as political and business news. The number one network in cable, FNC has been the most-watched television news channel for 18 consecutive years. According to a 2020 Brand Keys Consumer Loyalty Engagement Index report, FOX News is the top brand in the country for morning and evening news coverage. A 2019 Suffolk University poll named FOX News as the most trusted source for television news or commentary, while a 2019 Brand Keys Emotion Engagement Analysis survey found that FOX News was the most trusted cable news brand. A 2017 Gallup/Knight Foundation survey also found that among Americans who could name an objective news source, FOX News was the top-cited outlet. Owned by FOX Corporation, FNC is available in nearly 90 million homes and dominates the cable news landscape, routinely notching the top ten programs in the genre.
Watch full episodes of your favorite shows
The Five: https://www.foxnews.com/video/shows/the-five
Special Report with Bret Baier:
https://www.foxnews.com/video/shows/special-report
Jesse Watters Primetime:
https://www.foxnews.com/video/shows/jesse-watters-primetime
Hannity: https://www.foxnews.com/video/shows/hannity
The Ingraham Angle:
https://www.foxnews.com/video/shows/ingraham-angle
Gutfeld!: https://www.foxnews.com/video/shows/gutfeld
Fox News @ Night:
https://www.foxnews.com/video/shows/fox-news-night
Follow Fox News on Facebook:
https://www.facebook.com/FoxNews/
Follow Fox News on Twitter: https://twitter.com/FoxNews/
Follow Fox News on Instagram:
https://www.instagram.com/foxnews/
22:02
Trump is a savage for saying this: Kat Timpf "IndyWatch Feed Survival"
Fox News analyst Kat Timpf reacts to former President Donald Trump
explaining why he doesnt joke about President Bidens cognitive
abilities on Gutfeld!
Subscribe to Fox News! https://bit.ly/2vBUvAS
Watch more Fox News Video: http://video.foxnews.com
Watch Fox News Channel Live: http://www.foxnewsgo.com/
FOX News Channel (FNC) is a 24-hour all-encompassing news service delivering breaking news as well as political and business news. The number one network in cable, FNC has been the most-watched television news channel for 18 consecutive years. According to a 2020 Brand Keys Consumer Loyalty Engagement Index report, FOX News is the top brand in the country for morning and evening news coverage. A 2019 Suffolk University poll named FOX News as the most trusted source for television news or commentary, while a 2019 Brand Keys Emotion Engagement Analysis survey found that FOX News was the most trusted cable news brand. A 2017 Gallup/Knight Foundation survey also found that among Americans who could name an objective news source, FOX News was the top-cited outlet. Owned by FOX Corporation, FNC is available in nearly 90 million homes and dominates the cable news landscape, routinely notching the top ten programs in the genre.
Watch full episodes of your favorite shows
The Five: https://www.foxnews.com/video/shows/the-five
Special Report with Bret Baier:
https://www.foxnews.com/video/shows/special-report
Jesse Watters Primetime:
https://www.foxnews.com/video/shows/jesse-watters-primetime
Hannity: https://www.foxnews.com/video/shows/hannity
The Ingraham Angle:
https://www.foxnews.com/video/shows/ingraham-angle
Gutfeld!: https://www.foxnews.com/video/shows/gutfeld
Fox News @ Night:
https://www.foxnews.com/video/shows/fox-news-night
Follow Fox News on Facebook:
https://www.facebook.com/FoxNews/
Follow Fox News on Twitter: https://twitter.com/FoxNews/
Follow Fox News on Instagram:
https://www.instagram.com/foxnews/
22:00
Three Reasons Behind Bitcoin's 2023 Resurgence "IndyWatch Feed Crypto"
This is an opinion editorial by Chen Fang, the COO of BitGO, a Bitcoin-focused regulated custody and financial services firm.
A challenging 2022 prompted Bitcoin skeptics to gleefully say I told you so and declare that Bitcoin was dead and buried. But, much to their chagrin, their victory lap ended up being premature. Bitcoin has come roaring back in 2023, ending these premature celebrations and taking back some of its 2022 losses with a massive year-to-date gain of over 60% as of this writing so far in 2023.
Here are three reasons behind Bitcoins 2023 resurgence:
One: Banking Sector Turmoil And A Timely Reminder Of Bitcoins Value
In March 2023, turmoil from the banking sector in the wake of Silicon Valley Banks collapse rocked the market with the types of issues that it hadnt experienced since the Great Recession. This was no fly-by-night operation; at the time, Silicon Valley Bank (SVB) was the sixteenth-largest bank in the United States and the bank of choice for many venture capitalists and startups.
This high-profile implosion and the lack of proper risk management in place at SVB led many individuals to question how safe their money was. Ultimately, the Federal Reserve stepped in to make the banks depositors whole, but the event still called the health of the banking system into question.
While not everyone is rushing to take their money out of banks, many more people are now at least aware of the risks of a single point of failure and are moving to diversify their assets by splitting them between multiple banks or even diversifying into alternatives like bitcoin and other cryptocurrencies for the first time.
The appeal of a fully decentralized asset like bitcoin is that there is no CEO or management team in charge that can endanger the solvency of the Bitcoin network by making a bad decision or poor judgment call. Bitcoin users dont have to trust a company or management team to use Bitcoin; they can instead verify the open-source code that governs the Bitcoin network. Anyone can view any transaction ever made on the Bitcoin blockchain, giving the network unmatched transparency.
The price of bitcoin surged in March in the wake of the crisis, and in late April, renewed troubles at First Republic Bank, which reported that it...
21:45
21:28
5 free ChatGPT and generative AI courses "IndyWatch Feed Crypto"
Level up your skills in language models and automation with free ChatGPT and generative AI courses.
20:48
These Towns Will Actually Pay You to Move There "IndyWatch Feed Arts"
Youre telling me that the folks who run certain towns and cities are willing to actually PAY people to move there?
Well, thats a new one!
And if youve been looking for a change of scenery, you might want to consider one of these places that are handing out some pretty nice bonuses to folks looking to relocate.
Take a look at the list below and see if any of these places suit your fancy.
Topeka, Kansas
The capital city of Kansas will pay people up to $15,000 to move there if their employer participates in a specific program.
Theres an application process and you have to commit to living in Topeka for a year but there are also some employers that will match the money, so its possible to make double the money!
Look into it!
Paducah, Kentucky
Paducah is a small town of about 25,000 people and the folks in charge there are encouraging remote workers to make Paducah their home and theyll reward folks who choose the deal with a package thats...
20:43
The Lion of Chaeronea "IndyWatch Feed Literature"
Trifacial Trinity, anonymous artist (Cusco School), between ca. 1750 and ca. 1770
20:28
Christopher's Writing Thread "IndyWatch Feed Survival"
Hi
Amazon (and publishers) insist that I can't leave other copies of
my work on the net if I want to sell them, so I'm going to use this
thread to mention new books, promotions, etc. Please feel free to
watch and comment. . Or ask for a cameo ...
My website - Home
My Blog - The Chrishanger | Welcome to my Writing World please read
the 'about' page before proceeding.
My Facebook Fan Page...
Christopher's Writing Thread
19:39
Silver colored spheres Sometimes they are semi-translucent. New York Times, 14 December 1944 "IndyWatch Feed Spiritual"
18:59
Pro-XRP attorneys phone hacked to promote LAW token "IndyWatch Feed Crypto"
Lawyer John Deaton alerted followers via his daughters account, urging people to report the hack as the XRP community responded, spreading awareness.
18:48
Let sleeping dogs lie or face sandy vengeance "IndyWatch Feed Satire"
Someone named u/Classic_Oven12 has re-shared this classic clip of instant karma via dog.
To remove a dog by kicking
by u/Classic_Oven12 in therewasanattempt
Since so many Redditors hadnt seen it before, we thought wed give it another run-out, too. Especially after we spotted these replies.
Hes building a sandcasshole.
bumjiggy
Damn, the dog had to show her how its done properly.
PsychologicalBooks819
Learning valuable life lessons.
CatsMustDie
The punishment fits the crime.
foreverdonefor
Thats what you get when you mess with an earth bender
GimliSonOfGloin
Smart dog good boy!
Aggressive_Wasabi_38
Dog 1 Human 0.
AII for nothing
I feel like they worked it out in their own way.
Throwaway64
I think the parent is saying f**k around find out as they are shooting.
CoupwalObiWan
My dog would just kick her back.
This dog got hilariously creative.
Dfu4ever
Grentis noticed something about the girl.
Slowest getaway ever.
READ MORE
Watch this adorable dog trick herself into thinking theres somebody at the door
Source r/therewasanattempt Image Screengrab
The post Let sleeping dogs lie or face sandy vengeance appeared first on The Poke.
18:22
Cult Conspiracy: US Charges Two in Plot Against Chinese Religious Group "IndyWatch Feed Spiritual"
Two Chinese nationals allegedly acting as agents for the Chinese government were apprehended in the United States following an undercover operation and were charged with trying to damage and topple an anti-communist Chinese religious group.
US charges two over China-backed plot against Falun Gong https://t.co/Rk9UhxXN4v
Al Jazeera English (@AJEnglish) May 27, 2023
Authorities in Los Angeles arrested 70-year-old John Chen and 43-year-old Lin Feng on May 26th, where they were indicted for planning to revoke the tax-exempt status of the New York-based Falun Gong spiritual movement in an attempt to further undermine the exiled group.
The two Chinese nationals were both born in China but lived in Los Angeles at the time of their arrest. Chen is a US citizen, while Feng was described as a lawful permanent resident. Theyre facing charges of being unregistered agents of a foreign government, practicing money laundering, and bribing public officials.
Two Los Angeles residents were arrested for allegedly taking part in a Beijing-directed scheme to disrupt U.S.-based practitioners of Falun Gong, a spiritual movement banned in China for its criticism of the Chinese government https://t.co/gO1Z5rduVi pic.twitter.com/e5yE39uO1q
Reuters (@Reuters) May 27, 2023
Chen and Feng were caught after they initially urged the Internal Revenue Service (IRS) to revoke Falun Gongs non-profit tax status. Chen also described the organization as a gigantic mega cult in his whistleblower complaint that he filed to the tax agency last February, echoing the language used by the Chinese Communist Party (CCP) against the group.
After filing their complaint, an undercover police officer posed as an official for the IRS. According to prosecutors handling their case, Chen met with the officer at a restaurant north of New York City on May 14th.
Chen approached the officer to ensure that the agency would act on their complaint while communicating with h...
18:18
17:47
He Scolded Her For Her Swimsuit Choice. Is There Any Hope For Their Relationship? "IndyWatch Feed Arts"
Let me tell you a secret, everyone not all relationships are meant to last forever. There is no shame in calling it quits early on, either, if you realize your values, morals, or other preferences just dont align.
OP here is from a strict Muslim background, though he claims to be not that religious himself. He mentions that his girlfriend is American and not the modest kind, which has caused a few awkward bumps in what he describes as an otherwise smooth road.
So me (26M) and my Girlfriend (22F) have been dating for around 2 years now. Weve had our ups and downs but overall we have a great relationship, and I definitely see a future together! We really love and respect each other and connect well! But the thing is we come from different backgrounds. I come from a Muslim Background (Im not that religious tho) and she is White. However, we have still made it work and our similarities are much more than our differences.
Now my gf does like wearing a bit short clothing when out and about, which used to bother me at first and made me uncomfortable and we did have a few minor fights over it, but eventually I came to terms with it.
Recently they had a bump that he describes as a bit embarrassing, and it happened at his familys pool party.
He spoke with her ahead of time about making a modest bathing suit choice, and so was shocked to see her arrive in a cheeky bikini. OP was so mortified he couldnt look at or speak to his family!
However, recently an embarrassing situation happened. There was a pool party at my cousins house, and my parents were there too. I had recently introduced my gf to my parents as well, so this was a good time for to meet family and relatives. I specifically told her to please pack somet...
17:15
Punk Boy Scout Helps Elderly Woman Across Open Pit "IndyWatch Feed Satire"
OCEANVIEW, Ill. Local sixth-grade do-gooder Richie Amweather reportedly risked his own well-being at last nights hardcore show in order to help a geriatric woman across the pit, heartwarmed sources confirmed.
Speaking as a dedicated member of Troop 138, I thought not only was it the right thing to do, but it would count a long way toward being awarded the Pit Etiquette merit badge Ive been going for the past year. So, I offered my arm the instant I saw her narrowly avoid getting crowd punched, said 11-year-old Amweather. Sure, I got elbowed in the face a couple dozen times, and I got five or six tall boys spilled on my dry-clean only uniform, but it was all worth it to know that sweet old lady was safe from harms way. And the pat on the head she gave me after? Icing on the cake, yes sir!
The elderly woman in question, Ms. Lilac McMurtree, was reportedly more than appreciative for the scouts assistance.
Oh, that sweet young man gives me hope for the future. I wandered in after my trip to the greengrocer, intrigued by the look of the young combo on stage yelling fuck this and fuck that. I had never seen an amplifier colored orange, and wanted to get a closer look, said the 83-year-old retired sheet music store employee. With my hearing aid out of battery, I relied on little Richies guidance to get me up past the fine people kneeing each other in the back. I tried to give him a shiny nickel later to get himself an EP at the merch table, but he refused, saying doing good was its own reward.
Naming the program after his favorite krautrock band, Scout Master Wilson Hauer elaborated further on the Neu! Scout ethos.
That Amweather boy is turning into a fine young punk. Oughta complete Neu! Scouts at the top of his troop, said Hauer, while casually fashioning a microphone out of a stolen payphone receiver. Especially if he sells enough of my bands demo tapes outside the mini-mart come fundraising time. I tell you, these kids may not be old enough to get into a lot of the venues our trips take us to, but the xs on their hands are no match for the ps and qs they learn to always mind.
At press time, Amweather has decided next to receive his community service badge by cleaning the venue bathroom, which he hopes to complete by late 2026.
The post Punk Boy Scout Helps Elderly Woman Across Open Pit appeared first on The Hard Times.
17:13
Every Circle Jerks Album Ranked "IndyWatch Feed Satire"
As much fun as it was for me rank all these albums, I was skeptical at what an SEO nightmare it was going to be for me to have my name featured so prominently beside terms like Group Sex Golden Shower and the six dozen times I had to use the phrase Circle Jerks But, luckily for you, I manned up, swallowed my pride, and banged this out (ah jeez.) Anyway, whether you just know them from their self-deprecating cameo as the lounge band in Repo Man or respect them to the ends of the earth for solidifying the L.A hardcore sound, The Circle Jerks are punk legends for a damn good reason. And Im more than happy to destroy my reputation to future employers who may be Googling me on their behalf.
6. Wnderful (1985)
One of two albums of theirs that clocks in at over 30
minutes, and you know what they say: if a Circle Jerks record lasts
longer than a half hour, consult a physician immediately. Though
its got some fun stuff going on at various points the Seven
Dwarfs-esque whistling on the hook of the title track, and that
magnificent country-fried guitar solo on Mrs. Jones come to mind it
just isnt up to the snotty, rabid standard we know these fellas are
capable of. At the end of the day, Wnderful is a tad
nderwhelming.
Play It Again: Dude
Skip It: 15 Minutes
5. Oddities Abnormalities and Curiosities (1995)
Known as the only major label release from our boys,
were going to dub this not the worst due to the sheer
experimentation. After almost a decade of not recording, these
fellows could have gone full dad-reunion mode and gone through the
motions, but hell, they let Zander Schloss play the sitar on this
thing, so who are we to rank it last? Theyre t...
17:05
Opinion: Quiet Confidence Has Nothing on Loud Insecurity "IndyWatch Feed Satire"
Spend enough time scrolling through Instagram or aimlessly clicking through Pinterest boards and youll see all kinds of advocacy for something called quiet confidence, where you recognize your strengths and feel comfortable in yourself without needing to prove to anyone else that you have value. Now thats all well and good for the wake up at 6, in bed by 10 crowd, but I tried quiet confidence and let me tell you, it pales compared to the rush of loud insecurity.
I was telling my therapist about how any criticism at work eats away at me to the point that Im running back and forth to the bathroom to soak paper towels in water to hide any signs of crying. She suggested I do some journaling to help me untangle my negative thought patterns. Now, I cant say this didnt work because I didnt bother trying it. Instead, I loudly mentioned every mistake made by my coworkers to help deflect any criticism. This has yielded far more satisfying results.
This isnt limited to the workplace. Ive also harnessed this power to turn all my interpersonal relationships into one-sided pleas for validation that inevitably implode when the other person has enough of me bringing up that I was wait-listed at Dartmouth any time Im around someone who I perceive to be smarter than me. Did I get in? Nope. But that doesnt mean I cant name-drop an Ivy League school to help puff up my ego for a minute!
I also have to shout out the internet and social media for making it so easy to broadcast my debilitating lack of self-esteem. After all, what better way to scrutinize my worth as a human than by giving me an endless number of platforms to express how I have no conception of myself as anything but a vessel for others scorn? And if I dont get enough likes on a post, Ill definitely follow it up with another one directly pleading for attention. How many is enough? I still dont know!
But heres what I do know: loud insecurity has helped me to realize my lifes purpose, which is to try and do all I can to be recognized as worthwhile and desirable without any sort of willingness to reflect on my flaws and work to change them through consistent effort. Thats pretty special, right?
Right?
RIGHT???
The post Opinion: Quiet Confidence Has Nothing on Loud Insecurity appeared first on The Hard Times.
17:05
Ex-Hardcore Guitarist Who Joined the Worst Fucking Bar Rock Band Anyones Ever Heard Actually Seems Way Happier Now "IndyWatch Feed Satire"
BOSTON Bernie Callahan, ex-guitarist for local hardcore band Scald, is now performing with objectively horrendous bar rock band Tough N Stuff and thoroughly enjoying himself, sources feeling betrayed report.
Im pretty sure that Steve from Woeful is going to absolutely drag me as soon as he sees this, but thats fine, said Callahan while learning how to play Lits My Own Worst Enemy. But he doesnt understand Im finally playing music people actually enjoy. People say nice set to me and actually mean it. Not to mention I just got paid twice as much as that band made last year combined, and I get to go to bed before midnight. Not to mention Ive been able to cut back my therapy sessions to twice a month. Thats just more money in the bank.
Local promoter Claudine Osbourse allegedly saw Callahan smiling for the first time in 12 years while playing uninspired covers of The Rolling Stones and Santana.
I can barely believe its the same guy, said Osborne while sulkily smoking a cigarette. He used to be in the most pissed off hardcore band Ive ever seen. And whenever he got off stage he was even worse, just absolutely furious every show that not enough people showed up or moshed hard enough. But when he got to do the background vocals for that AC/DC cover the other night, that was probably the first time I have ever seen him legitimately enjoying himself. I think Im proud of him?
While most are voicing their support for Callahans decision to prioritize his own mental health, some have criticized the guitarists musical 180.
The guy is just torpedoing his career, said local music critic Carlene Gibbs. With this new band, there is absolutely no way he will ever gain any influence or notoriety beyond his local community. But if he had stuck with Scald for another seven or so years, he would have had a chance to reach upwards of sixty people in four or five counties. Weve lost an entire generation of perhaps a dozen resentful and unfulfilled musicians who would have started as their base. No question.
At press time, Callahan has reportedly gotten laid after a gig for the first time in his musical career.
The post Ex-Hardcore Guitarist Who Joined the Worst Fucking Bar Rock Band Anyones Ever Heard Actually Seems Way Happier Now appeared first on The Hard Times.
16:44
Mens begrijpen helaas niet hoe dit corrupte systeem werkt. "IndyWatch Feed Uncanny"
https://www.de-nieuwe-media.nl/l/jaap-bottenberg-gerechtsdeurwaarder-mededirecteur-en-eigenaar-van-syncasso-in-groningen-pleegde-illegale-praktijken-en-werd-een-oplichter-genoemd/ Mens begrijpen helaas niet hoe dit corrupte systeem werkt. Alles wat legaal is is per definitie niet wettig en dus fraude, valsheid in geschrifte, dwang, dwaling, afpersing, oplichting, meineed Continue Reading
Het bericht Mens begrijpen helaas niet hoe dit corrupte systeem werkt. verscheen eerst op Take care 4.
16:27
FTX debtors object to Genesis critical claims estimate of $0.00 "IndyWatch Feed Crypto"
The FTX debtors alleged that the claim was filed without any advance notice, and they were not invited to participate in the mediation.
16:02
Theresa in all the ruffles "IndyWatch Feed Craft"
Whenever my dear friend Theresa comes to Wellington we dress up together and do a photoshoot. Weve been doing this for 12 years now!
She was here back in April, and I offered her a whole range of things from my historical wardrobe, but obviously she picked the 1760s frou frou francaise. I mean, who wouldnt?
Its silk taffeta covered in ruffles and lace, and theres an equally ruffly Marie Mantle to pair with it. Whats not to love?
And doesnt she look spectacular in it!
Also, Im very proud of what I achieved with her hair. I think its my best attempt at late 1760s/early 1770s hair yet. I still feel like its more accident than actual learned skill when I get 18th c hair right, but every time I do it it gets a little bit better.
For the photoshoot, we went up to the Sir Truby King gardens, which are is still one of my favourite places to take...
15:43
Raising Ducks and Chickens "IndyWatch Feed Survival"
Now I'm just the tech and message / poster here .
The 2 Ladies who run the farm / ranch know more that I .
I built the incubator from old fridge and brooder .
Later this week the ducks will hatch , then the chicken eggs go in
. I'll keep updating this thread.
Automatic controls , top 37.C is temp freezer section ,78.3 is
humidity ,34.8 is lower temp of the fridge and its on warming up
.
Sloth
14:57
Bedrock Upgrade: How Optimism Game-Changer Could Impact OP Price "IndyWatch Feed Crypto"
Optimism is gearing up for its eventual mainnet upgrade next week. This upgrade will offer lower protocol and security fees for users on the platform. This led to the ecosystems governance token, OP, enjoying an increase in price, albeit a modest 3.7% in the past 24 hours.
This price movement only came after last months dismal performance where OP dropped by over 30% in the monthly timeframe.
With the promise of lower fees along with Ethereum-like security for the coming upgrade, we might see OP continue its present bullishness.
Optimism: Laying The Bedrock For Future Growth
Touted as the Bedrock mainnet upgrade, it aims to improve efficiency to drive down costs for investors on the platform. According to Optimisms recent blog post, it should be able to drive protocol and security costs by a whopping 47%. The upgrade will use channels that will be split again to further optimize data compression.
Layer2 network Optimism is gearing up for the Bedrock Upgrade soon!
Discover how this game-changing update boosts scalability, security, and efficiency for Optimism, and what it means for the future of #Ethereum.#Optimism $OP #Layer2 #EIP1559
KuCoin (@kucoincom) June 2, 2023
This upgrade also corresponds to Ethereums Dencun upgrade, which will drive down on-chain costs as a result of danksharding. Danksha...
14:56
People Shared The Very Real Downsides To Being Super Attractive "IndyWatch Feed Arts"
When were young, human beings tend to think that if they could choose whether or not to be attractive, they would definitely opt in. Prettiness/Handsomeness is a type of currency and has been proven to give people a natural advantage pretty much everywhere.
That said, there are always downsides to every upside, and you can never know what its like living as someone else unless they tell you.
These pretty people have some complaints to lodge, so take a look.
That is assault.
Being groped, grabbed, etc. when youre out just trying to have fun with your friends.
I literally had a guy come up behind me at a urinal, reach around and grab my d*%k .
Thats what depression is.
Ive been told you won the genetic lottery. What do you have to be depressed about?
Mf thats what depression is. Its not about s*%t.
Complete and total.
Complete and total objectification.
It leaves you feeling as if you are never seen or even appreciated for who you are as a person, and is also why many attractive people struggle mentally.
Thats not how this works.
Im an autistic woman but, according to everyone else I cant be cuz I dont look autistic.
As if autistic people cant be pretty lol.
Pros and cons.
Background: I was never unattractive, but three years or so ago I lost 45 pounds (not on purpose horrible depressive episode) and that pushed me a lot closer to societys beauty standard.
Its also important to note that for women (and men too but to a lesser e...
14:28
Centella asiatica and its metabolite asiatic acid: wound healing effects. "IndyWatch Feed Health"
PMID: Metabolites. 2023 Feb 14 ;13(2). Epub 2023 Feb 14. PMID: 36837896 Abstract Title: and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential. Abstract: An intense effort has been focused on new therapeutic approaches and the development of technologies for more efficient and rapid wound healing. The research for plants used for long time in traditional medicine in the treatment of wound has become a promising strategy to obtain drugs therapeutically useful in the acute and chronic wound management. In this context,(Apiaceae) has been used to treat a variety of skin diseases, such as leprosy, lupus, varicose ulcers, eczema and psoriasis, in Asiatic traditional medicine for thousands of years. Studies have shown thatextracts (CAE) display activity in tissue regeneration, cell migration and wound repair process by promoting fibroblast proliferation and collagen synthesis. Preliminary findings have shown that the asiatic acid is one of the main active constituents of, directly associated with its healing activity. Thus, this study discusses aspects of the effects ofand its active component, asiatic acid, in different stages of the healing process of cutaneous wounds, including phytochemical and antimicrobial aspects that contribute to its therapeutic potential.
14:01
Why the United States Will Fall "IndyWatch Feed Fertility"
This is why the United States is dead. It can no longer stand united and, like Ukraine, we too will simply have to split. There should be a property swap where Democrats leave the Red States and go to the Blue States and vice versa. This is how empires always die. They collapse from an internal division that eats away at them from within like cancer. Hayley Williams has only shown how she is brainwashed into thinking that abortion is a womans right when it was a Gates-Rockafeller ploy to further eugenics and reduce the population of minorities.
Justice Ginsberg was a womans activist. She explained that Roe v Wade was not about womens rights. It was about eugenics. So they get women to agree to war and whatever because all they can focus on is abortion which was a lie, to begin with.
You cannot allow one side to force their beliefs upon the ot...
14:00
Bitcoin and United States Dollar "IndyWatch Feed Crypto"
0.00010 BTC = 2.72 USD
1.00 USD = 0.00004 BTC
Converter
13:41
Pecking Away "IndyWatch Feed Health"
By Cathy Jameson
A few times over the last few weeks Ive seen 2 or 3 smaller birds flying after a larger black bird. The smaller birds are adamantly pecking. Called mobbing, the large bird ends up flying off, getting away from the much smaller ...
12:57
An Airbnb Host Noticed That Someone Stole a Painting From Her Rental and Replaced It With a Different One "IndyWatch Feed Arts"
Photo Credit: TikTok
Being an Airbnb host has to be pretty weird because you never know who youre renting your place out to
And heres another story that illustrates that point in a major way!
An Airbnb host found out that one of her guests stole one of the paintings off the wall of her rental unit and replaced it with a totally different painting.
So naturally, she shared a story about it on TikTok.
12:50
The effect of Centella Asiatica cream on scar development in patients who underwent open carpal tunnel release surgery. "IndyWatch Feed Health"
PMID: J Hand Ther. 2023 Mar 12. Epub 2023 Mar 12. PMID: 36918311 Abstract Title: The effect of Centella Asiatica cream on scar development in patients who underwent open carpal tunnel release surgery. Abstract: AIM: To evaluate the efficacy of the Centella asiatica extract in a cream preparation for the prevention of scar tenderness formation in patients who underwent conventional open carpal tunnel release (CTR) surgery.MATERIAL AND METHODS: A total of 280 patients with carpal tunnel syndrome who underwent CTR surgery were individually randomized into the intervention (n = 140) and control (n = 140) groups. In the intervention group, a petroleum cream mixture consisting of 1% Centella asiatica extract was applied to the patients' wrist for 6 months after the sutures were removed. In the control group, no intervention was applied. The Vancouver Scar Scale (VSS), Quick Disabilities of Arm, Shoulder and Hand (QuickDASH) functional score, and Visual Analog Scale (VAS) satisfaction scores were assessed preoperatively and postoperatively. Follow-up evaluations were scheduled at 1, 3 and 6 months after CTR surgery.RESULTS: The overall VSS score of the intervention group significantly improved at 3-6 months (-1.260, p = .040). At 6 months after surgery, the mean QuickDASH functional score was 18.54 (range 0.00-63.64, SD 17.4) in the intervention group and 28.7012 (range: 2.27-40.91) in the control group (p
12:37
Elliptic integrates ChatGPT to bolster crypto risk detection "IndyWatch Feed Crypto"
Crypto risk management firm Elliptic believes ChatGPT will assist in scaling up intelligence and expose risks to crypto users that they cant get anywhere else.
12:12
Monotherapy with a non-hormonal Centella asiatica, hyaluronic acid, and prebiotic-based vaginal gel in women with bacterial vaginosis. "IndyWatch Feed Health"
PMID: Clin Med Insights Case Rep. 2023 ;16:11795476231157244. Epub 2023 Feb 23. PMID: 36860213 Abstract Title: Monotherapy With a Non-Hormonal Centella Asiatica, Hyaluronic Acid, and Prebiotic-Based Vaginal Gel in Women With Bacterial Vaginosis: Case Series. Abstract: Bacterial vaginosis (BV) affects nearly one-third of women worldwide and may predispose patients to sexually transmitted infections or pelvic inflammatory disease. Currently recommended treatment is based on antibiotic use, which poses problems such as antibiotic resistance and the development of secondary vaginal candidiasis. Palomacareis a non-hormonal vaginal gel containing hyaluronic acid,and prebiotics, with repairing and moisturizing properties used for dysbiosis healing as an adjuvant treatment. A series of 3 cases using the vaginal gel as a monotherapy showed that symptoms improved and even disappeared in women with initial or recurrent BV, suggesting that this vaginal gel is effective for BV monotherapy in women of reproductive age.
12:09
Standardized extract of Centella asiatica prevents fear memory deficit. "IndyWatch Feed Health"
PMID: Am J Chin Med. 2023 ;51(2):329-353. Epub 2023 Jan 25. PMID: 36695831 Abstract Title: Standardized Extract ofPrevents Fear Memory Deficit in 3xTg-AD Mice. Abstract: ECa 233 is a standardized extract of(CA), an herb widely used in traditional Chinese and Ayurvedic medicine. Previous studies reported that ECa 233 enhanced memory retention and synaptic plasticity in the hippocampus of healthy rats. Because of this, we became curious whether ECa 233 has a therapeutic effect on the fear memory deficit in the triple transgenic Alzheimer's disease (3xTg-AD) model mice. Fear memory is a crucial emotional memory for survival that is found to be impaired in patients with early-onset Alzheimer's disease (AD). In this study, we orally administered ECa 233 (doses: 10, 30, and 100[Formula: see text]mg/kg) to 3xTg-AD mice, who were five months old, for 30 consecutive days. We found that ECa 233 prevented a cued fear memory deficit and enhanced hippocampal long-term potentiation (LTP) in 3xTg-AD mice. Subsequent proteomic and western blot analyses revealed increased expression levels of the molecules related to LTP induction and maintenance, including brain-derived neurotrophic factor (BDNF), tyrosine receptor kinase B (TrkB) and its network proteins, and extracellular signal-regulated kinase 1 and 2 (ERK1 and 2) in the hippocampi and amygdala of 3xTg-AD mice after ECa 233 pre-treatment. Our results indicate that ECa 233 is a promising potential herbal standardized extract that could be used in preventing the fear memory deficit and synaptic dysfunction before the early onset of AD.
12:05
Cannabidiol as a promising adjuvant therapy for estrogen receptor-positive breast tumors. "IndyWatch Feed Health"
PMID: Cancers (Basel). 2023 Apr 27 ;15(9). Epub 2023 Apr 27. PMID: 37173983 Abstract Title: Cannabidiol as a Promising Adjuvant Therapy for Estrogen Receptor-Positive Breast Tumors: Unveiling Its Benefits with Aromatase Inhibitors. Abstract: BACKGROUND: Estrogen receptor-positive (ER) breast cancer is the most diagnosed subtype, with aromatase inhibitors (AIs) being one of the therapeutic drug types used in the clinic. However, endocrine resistance may develop after prolonged treatment, and different approaches, such as combining endocrine and targeted therapies, have been applied. Recently, we demonstrated that cannabidiol (CBD) induces anti-tumor actions in ERbreast cancer cells by targeting aromatase and ERs. Considering this, we studied, in vitro, whether CBD when combined with AIs could improve their effectiveness.METHODS: MCF-7aro cells were used and the effects on cell viability and on the modulation of specific targets were investigated.RESULTS: CBD when combined with anastrozole (Ana) and letrozole (Let) caused no beneficial effect in comparison to the isolated AIs. In contrast, when combined with the AI exemestane (Exe), CBD potentiated its pro-cell death effects, abolished its estrogen-like effect, impaired ERactivation, and prevented its oncogenic role on the androgen receptor (AR). Moreover, this combination inhibited ERKactivation, promoting apoptosis. The study of the hormonal microenvironment suggests that this combination should not be applied in early stages of ERbreast tumors.CONCLUSIONS: Contrary to Ana and Let, this study highlights the potential benefits of combining CBD with Exe to improve breast cancer treatment and opens up the possibility of new therapeutic approaches comprising the use of cannabinoids.
11:54
Hello! "IndyWatch Feed Survival"
Hello from this side of the world!
11:10
Welcome To Craft Schooling Sunday! "IndyWatch Feed Craft"
Thanks so much for joining me here, please share your latest, I'm off to bed, but will write something here tomorrow. Loving this DIY reusable lunch bag from hello sewing. Fun crocheted chenille cat and love that yarn bowl, from...
10:59
The Nervous System in the Classroom | Gary Sharpe "IndyWatch Feed Health"
From Gary Sharpe: The work of Dr Stephen Porges, and his Polvagal Theory, was instrumental in my own understanding and knowledge of the Nervous System, chronic illness and trauma, and from there, the human condition, and societal issues. It is what led me to glean that my own Idiopathic Parkinsons Disease diagnosis was actually me being stuck in the freeze or tonic immobility stress response.
Porges basic tenet is that our Nervous System is constantly evaluating the environment for cues of threats or safety, through a danger sense he calls neuroception. If our neuroception deems the situation to be safe, we can be in calm, relaxed, and socially engaged states. If it deems there is a threat, it activates fight or flight responses, or if the danger is perceived as sufficiently great, puts us into a state of freeze.
Note here the use of the term safe has nothing to do with health & safety or safe spaces it means feeling safe at a visceral, Nervous System level.
Porges has used his work as a lens to look at various aspects of modern life, such as the design of schools and hospitals, and found them wanting. Indeed, through this lens, many of our institutions seem almost designed to constantly trigger our sense of threat.
In his 2011 interview The Polyvagal Theory, Somatic Perspectives, Porges puts education systems and schools under the spotlight of his Nervous Systems work, explaining why modern schooling and educational methods are at odds with healthy Nervous System functioning. Here, we work through this important work.
However, even though we are discussing the classroom, for me the direct analogies carry over in a very straightforward way to any and all of our institutions where some folks have control or power over the lives of others. For example we could have talked about prisons, where we can straightforwardly swap out teacher for prison guard, and child for prisoner, or corporate employment, where we swap teacher for manager/boss, and child for employee, hospitals/healthcare (doctor and patients), government (elected politician and electorate), or caregiving (caregiver and cared for).
...
10:58
The Lion of Chaeronea "IndyWatch Feed Literature"
Starry Night Over the Rhone, Vincent van Gogh, 1888
10:54
Here's a pattern for a running belt with pockets and an elasticized adjustable strap so you can tailor it to any waist size. This pouch could also be called a money belt, travel belt or sports belt. Place the pouch on your front or back and cover it with a Continue reading
10:49
Efficacy of cannabidiol in convulsive and nonconvulsive seizure types associated with treatment-resistant epilepsies. "IndyWatch Feed Health"
PMID: Epilepsia. 2023 May 26. Epub 2023 May 26. PMID: 37243404 Abstract Title: Efficacy of cannabidiol in convulsive and nonconvulsive seizure types associated with treatment-resistant epilepsies in the expanded access program. Abstract: Cannabidiol (CBD) Expanded Access Program (EAP), initiated in 2014, provided CBD (Epidiolex) to patients with treatment-resistant epilepsy (TRE). In the final pooled analysis of 892 patients treated through January 2019 (median exposure 694days), CBD treatment was associated with a 46%-66% reduction in median monthly total (convulsive plus nonconvulsive) seizure frequency. CBD was well tolerated, and adverse events were consistent with previous findings. We used pooled EAP data to investigate the effectiveness of add-on CBD therapy for individual convulsive seizure types (clonic, tonic, tonic-clonic, atonic, focal to bilateral tonic-clonic) and nonconvulsive seizure types (focal with and without impaired consciousness, absence [typical and atypical], myoclonic, myoclonic-absence) and epileptic spasms. CBD treatment was associated with a reduction in the frequency of convulsive seizure types (median percentage reduction, 47%-100%) and nonconvulsive seizure types and epileptic spasms (median percentage reduction, 50%-100%) across visit intervals through 144weeks of treatment. Approximately 50% of patients had50% reduction in convulsive and nonconvulsive seizure types and epileptic spasms at nearly all intervals. These results show a favorable effect of long-term CBD use in patients with TRE who may experience various convulsive and nonconvulsive seizure types. Future controlled trials are needed to confirm these findings.
10:47
Cannabidiol improves muscular lipid profile by affecting the expression of fatty acid transporters and inhibiting de novo lipogenesis. "IndyWatch Feed Health"
PMID: Sci Rep. 2023 Mar 6 ;13(1):3694. Epub 2023 Mar 6. PMID: 36879113 Abstract Title: Cannabidiol improves muscular lipid profile by affecting the expression of fatty acid transporters and inhibiting de novo lipogenesis. Abstract: Obesity is one of the principal public health concerns leading to disturbances in glucose and lipid metabolism, which is a risk factor for several chronic diseases, including insulin resistance, type 2 diabetes mellitus, and cardiovascular diseases. In recent years, it turned out that cannabidiol (CBD) is a potential therapeutic agent in the treatment of obesity and its complications. Therefore, in the present study, we used CBD therapy (intraperitoneal injections in a dose of 10 mg/kg of body mass for 14 days) in a rat model of obesity induced by a high-fat diet (HFD). Gas-liquid chromatography and Western blotting were applied in order to determine the intramuscular lipid content and total expression of selected proteins in the white and red gastrocnemius muscle, respectively. Based on fatty acid composition, we calculated de novo lipogenesis ratio (16:0/18:2n-6), desaturation ratio (18:1n-9/18:0), and elongation ratios (18:0/16:0, 20:0/18:0, 22:0/20:0 and 24:0/22:0), in the selected lipid fractions. Two-week CBD administration significantly reduced the intramuscular fatty acids (FAs) accumulation and inhibited de novo lipogenesis in different lipid pools (in the free fatty acid, diacylglycerol, and triacylglycerol fractions) in both muscle types, which coincided with a decrease in the expression of membrane fatty acid transporters (fatty acid translocase, membrane-associated fatty acid binding protein, and fatty acid transport proteins 1 and 4). Moreover, CBD application profoundly improved the elongation and desaturation ratios, which was in line with downregulated expression of enzymes from the family of elongases and desaturases regardless of the metabolism presented by the muscle type. To our knowledge, this study is the first that outlines the novel effects of CBD action on skeletal muscle with different types of metabolism (oxidative vs. glycolytic).
10:45
Cannabidiol improves haloperidol-induced motor dysfunction in zebrafish. "IndyWatch Feed Health"
PMID: J Cannabis Res. 2023 Mar 4 ;5(1):6. Epub 2023 Mar 4. PMID: 36871008 Abstract Title: Cannabidiol improves haloperidol-induced motor dysfunction in zebrafish: a comparative study with a dopamine activating drug. Abstract: BACKGROUND: Cannabidiol (CBD) extracted from the cannabis plant is believed to have a medicinal value due to its neuroprotective effect via anti-inflammatory and antioxidant action. Recent behavioral studies in rats have reported that CBD mediates serotonin (5-HT1A) receptor action to improve motor dysfunction induced by dopamine (D2) receptor blockade. In particular, its effect on D2 receptor blockade in the striatum is an important function associated with neurological disorders resulting from various extrapyramidal motor dysfunctions. Dopaminergic neurodegeneration associated with this site is known for inducing Parkinson's disease (PD), which often affects the elderly. It is also known to cause drug-induced Parkinsonism. This study examines the ameliorating effect of CBD, which does not act directly on D2 receptors, against drug-induced motor dysfunction induced by the antipsychotic drug (haloperidol).METHODS: We created a drug-induced Parkinsonism model in zebrafish larvae using an antipsychotic drug (haloperidol). We evaluated the distance traveled and repetitive light-stimulation response. Furthermore, we examined whether administration of several concentrations of CBD ameliorates symptoms of the Parkinsonism model and compared its effects with those of antiparkinsonian drug ropinirole.RESULTS: CBD concentrations equal to half of haloperidol's resulted in an almost complete reversal of haloperidol-induced motor dysfunction, as measured by the distance traveled by the zebrafish and their response to light-stimulus. While ropinirole also significantly reversed haloperidol's effects at the same concentration as CBD, CBD was more effective than ropinirole.CONCLUSIONS: CBD-induced motor dysfunction improvement via D2 receptor blockade is a potential novel mechanism for the treatment of haloperidol-induced motor dysfunction.
10:43
Anticancer properties of cannabidiol and 9-tetrahydrocannabinol and synergistic effects with gemcitabine and cisplatin in bladder cancer cell lines. "IndyWatch Feed Health"
PMID: J Cannabis Res. 2023 Mar 4 ;5(1):7. Epub 2023 Mar 4. PMID: 36870996 Abstract Title: Anticancer properties of cannabidiol and-tetrahydrocannabinol and synergistic effects with gemcitabine and cisplatin in bladder cancer cell lines. Abstract: INTRODUCTION: With the legalization of cannabis in multiple jurisdictions throughout the world, a larger proportion of the population consumes cannabis. Several studies have demonstrated anti-tumor effects of components present in cannabis in different models. Unfortunately, little is known about the potential anti-tumoral effects of cannabinoids in bladder cancer and how cannabinoids could potentially synergize with chemotherapeutic agents. Our study aims to identify whether a combination of cannabinoids, like cannabidiol and-tetrahydrocannabinol, with agents commonly used to treat bladder cancer, such as gemcitabine and cisplatin, can produce desirable synergistic effects. We also evaluated if co-treatment with different cannabinoids resulted in synergistic effects.METHODS: We generated concentration curves with several drugs, including several cannabinoids, to identify the range at which they could exert anti-tumor effects in bladder cancer cell lines. We tested the cytotoxic effects of gemcitabine (up to 100 nM), cisplatin (up to 100 M), and cannabinoids (up to 10 M) in T24 and TCCSUP cells. We also evaluated the activation of the apoptotic cascade and whether cannabinoids have the ability to reduce invasion in T24 cells.RESULTS: Cannabidiol,-tetrahydrocannabinol, cannabichromene, and cannabivarin reduce cell viability of bladder cancer cell lines, and their combination with gemcitabine or cisplatin may induce differential responses, from antagonistic to additive and synergistic effects, depending on the concentrations used. Cannabidiol and-tetrahydrocannabinol were also shown to induce apoptosis via caspase-3 cleavage and reduce invasion in a Matrigel assay. Cannabidiol and-tetrahydrocannabinol also display synergistic properties with other cannabinoids like cannabichromene or cannabivarin, although individual cannabinoids may be sufficient to reduce cell viability of bladder cancer cell lines.DISCUSSION: Our results indicate that cannabinoids can reduce human bladder transitional cell carcinoma cell viability, and that they can potentially exert synergistic effects when combined with other agents. Our in vitro results will form the basis for future studies in vivo and in clinical trials for the development of new therapies that could be beneficial for the treatment of bladder cancer in the future.
10:40
Neuroprotection by the cannabidiol aminoquinone VCE-004.8 in experimental ischemic stroke in mice. "IndyWatch Feed Health"
PMID: Neurochem Int. 2023 May ;165:105508. Epub 2023 Feb 28. PMID: 36863495 Abstract Title: Neuroprotection by the cannabidiol aminoquinone VCE-004.8 in experimental ischemic stroke in mice. Abstract: Synthetic cannabidiol (CBD) derivative VCE-004.8 is a peroxisome proliferator-activated receptor gamma (PPAR) and cannabinoid receptor type 2 (CB) dual agonist with hypoxia mimetic activity. The oral formulation of VCE-004.8, termed EHP-101, possesses anti-inflammatory properties and is currently in phase 2 clinical trials for relapsing forms of multiple sclerosis. The activation of PPARor CBreceptors exerts neuroprotective effects by dampening neuroinflammation in ischemic stroke models. However, the effect of a dual PPAR/CBagonist in ischemic stroke models is not known. Here, we demonstrate that treatment with VCE-004.8 confers neuroprotection in young mice subjected to cerebral ischemia. Male C57BL/6J mice, aged 3-4 months, were subjected to 30-min transient middle cerebral artery occlusion (MCAO). We evaluated the effect of intraperitoneal VCE-004.8 treatment (10 or 20 mg/kg) either at the onset of reperfusion or 4h or 6h after the reperfusion. Seventy-two hours after ischemia, animals were subjected to behavioral tests. Immediately after the tests, animals were perfused, and brains were collected for histology and PCR analysis. Treatment with VCE-004.8 either at the onset or 4h after reperfusion significantly reduced infarct volume and improved behavioral outcomes. A trend toward reduction in stroke injury was observed in animals receiving the drug starting 6h after recirculation. VCE-004.8 significantly reduced the expression of pro-inflammatory cytokines and chemokines involved in BBB breakdown. Mice receiving VCE-004.8 had significantly lower levels of extravasated IgG in the brain parenchyma, indicating protection against stroke-induced BBB disruption. Lower levels of active matrix metalloproteinase-9 were found in the brain of drug-treated animals. Our data show that VCE-004.8 is a promising drug candidate for treating ischemic brain injury. Since VCE-004.8 has been shown to be safe in the clinical setting, the possibility of repurposing its use as a delayed treatment option for ischemic stroke adds substantial translational value to our findings.
10:39
Cannabidiol and Cannabis Sativa as a potential treatment in vitro prostate cancer cells. "IndyWatch Feed Health"
PMID: Mol Biol Rep. 2023 May ;50(5):4039-4047. Epub 2023 Feb 28. PMID: 36853473 Abstract Title: Cannabidiol and Cannabis Sativa as a potential treatment in vitro prostate cancer cells silenced with RBBp6 and PC3 xenograft. Abstract: BACKGROUND: Prostate cancer is the second most frequently occurring carcinoma in males worldwide and one of the leading causes of death in men around the world. Recent studies estimate that over 1.4 million males are diagnosed with prostate cancer on an annual basis, with approximately 375,000 succumbing to the disease annually. With current treatments continuing to show severe side effects, there is a need for new treatments. In this study we looked at the effect of cannabis sativa extract, cannabidiol and cisplatin on prostate cancer cells, PC3.METHODS: In addressing the above questions, we employed the MTT assay to measure the antiproliferative effect on PC3 cells following treatment with varying concentrations of Cannabis sativa extract, cisplatin and cannabidiol. xCELLigence was also used to confirm the IC50 activity in which cells were grown in a 16 well plate coated with gold and monitor cell attachment. Caspase 3/7 activity was also measured using 96 well-plate following treatment. Western-blot and qRT-PCR was also used to measure the gene expression of tumour suppressor genes, p53, Bax and Bcl2. Animal studies were employed to measure the growth of PC3-mouse derived cancer to evaluate the effect of compounds in vivo.RESULTS: From the treatment with varying concentrations of Cannabis sativa extract, cannabidiol and cisplatin, we have observed that the three compounds induced antiproliferation of PC3 cancer cell lines through the activation of caspase 3/7 activity. We also observed induction of apoptosis in these cells following silencing of retinoblastoma binding protein 6 (RBBP6), with upregulation of p53 and bax mRNA expression, and a reduction in Bcl2 gene expression. The growth of tumours in the mouse models were reduced following treatment with cisplatin and cannabidiol.CONCLUSION: We demonstrated that cannabidiol is a viable therapy to treat prostate cancer cells, in combination with silencing of RBBP6. This suggests that cannabidiol rather Cannabis sativa extract may play an important role in reducing cancer progression.
10:34
Whats Your Favorite Quote From South Park? Heres What People Said. "IndyWatch Feed Arts"
Its hard to believe that South Park has been on the air since FREAKING 1997.
But the show keeps chugging along and its fans have remained loyal for well over two decades.
And you and I both know that the program is chock-full of hilarious and memorable quotes, so lets check out some favorites from folks on AskReddit.
Every single time.
Eric Cartman : Alright, Token, give me a smooth bass line.
Tolkien Black : I dont know how to play bass.
Eric Cartman : Token, how many times do we have to go through this. Youre black. You can play bass.
Tolkien Black : Im getting sick of your stereotypes.
Eric Cartman : Be as sick as you want. Just gimme a goddamn bass line.
Tolkien proceeds to absolutely shred on the bass
Tolkien Black: .godda**it
That bit gets me every time.
Makes sense.
Jimmy: I lost my crutches!
Kyle: You have your crutches.
Jimmy: Its a saying among us crippled people. Wed say we lost an arm and a leg but they aint worth much.
Cartman: That makes sense.
I love life.
Butters: I love life.
Emo kids: Huh? But you just got dumped.
Butter: Yeah and Im sad.but at the same time Im really happy something can make me feel this sadits like it makes me feel alive, you know? It makes me feel human. The only way I can feel this sad now, is if I felt something really good before. So I have to take the bad with the good. So I guess what Im feeling is like a beautiful sadness.
Classy!
Im not having a glass of wine, Im having six.
Its cal...
10:32
The synergistic anticancer effect of CBD and doxorubicin in osteosarcoma. "IndyWatch Feed Health"
PMID: Clin Transl Oncol. 2023 Feb 27. Epub 2023 Feb 27. PMID: 36848028 Abstract Title: The synergistic anticancer effect of CBD and DOX in osteosarcoma. Abstract: BACKGROUND: Osteosarcoma is a malignant tumor that can present with pain in the bones, joints, and local masses. The incidence is highest in adolescents, and the most common sites are the distal femur, proximal tibia and proximal humerus metaphyseal. Doxorubicin is the first-line chemotherapeutic agent for the treatment of osteosarcoma, but it has many side effects. Cannabidiol is a non-psychoactive plant cannabinoid cannabinol (CBD) that has been shown to be effective against osteosarcoma; however, the molecular targets and mechanisms of CBD action in osteosarcoma remain unclear.METHODS: Cell proliferation, migration, invasion and colony formation were analyzed using two drugs alone or in combination to evaluate their inhibitory effects on the malignant characteristics of OS cells. Apoptosis and the cell cycle were detected by flow cytometry. The synergistic inhibitory effect of doxorubicin/cannabidiol on tumors was also detected in nude mouse xenotransplantation models.RESULTS: Through analysis of two osteosarcoma cell lines, MG63 and U2R, it was found that the cannabidiol/doxorubicin combination treatment synergistically inhibited growth, migration and invasion and induced apoptosis, blocking G2 stagnation in OS cells. Further mechanistic exploration suggests that the PI3K-AKT-mTOR pathway and MAPK pathway play an important role in the synergistic inhibitory effect of the two drugs in osteosarcoma. Finally, in vivo experimental results showed that the cannabidiol/doxorubicin combination treatment significantly reduced the number of tumor xenografts compared to cannabidiol alone or doxorubicin alone.CONCLUSIONS: Our findings in this study suggest that cannabidiol and doxorubicin have a synergistic anticancer effect on OS cells, and their combined application may be a promising treatment strategy for OS.
10:30
Effects of cannabidiol on innate immunity: experimental evidence and clinical relevance. "IndyWatch Feed Health"
PMID: Int J Mol Sci. 2023 Feb 4 ;24(4). Epub 2023 Feb 4. PMID: 36834537 Abstract Title: Effects of Cannabidiol on Innate Immunity: Experimental Evidence and Clinical Relevance. Abstract: Cannabidiol (CBD) is the main non-psychotropic cannabinoid derived from cannabis (L., fam. Cannabaceae). CBD has received approval by the Food and Drug Administration (FDA) and European Medicines Agency (EMA) for the treatment of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome. However, CBD also has prominent anti-inflammatory and immunomodulatory effects; evidence exists that it could be beneficial in chronic inflammation, and even in acute inflammatory conditions, such as those due to SARS-CoV-2 infection. In this work, we review available evidence concerning CBD's effects on the modulation of innate immunity. Despite the lack so far of clinical studies, extensive preclinical evidence in different models, including mice, rats, guinea pigs, and even ex vivo experiments on cells from human healthy subjects, shows that CBD exerts a wide range of inhibitory effects by decreasing cytokine production and tissue infiltration, and acting on a variety of other inflammation-related functions in several innate immune cells. Clinical studies are now warranted to establish the therapeutic role of CBD in diseases with a strong inflammatory component, such as multiple sclerosis and other autoimmune diseases, cancer, asthma, and cardiovascular diseases.
10:28
Cannabidiol: bridge between antioxidant effect, cellular protection, and cognitive and physical performance. "IndyWatch Feed Health"
PMID: Antioxidants (Basel). 2023 Feb 14 ;12(2). Epub 2023 Feb 14. PMID: 36830042 Abstract Title: Cannabidiol: Bridge between Antioxidant Effect, Cellular Protection, and Cognitive and Physical Performance. Abstract: The literature provides scientific evidence for the beneficial effects of cannabidiol (CBD), and these effects extend beyond epilepsy treatment (e.g., Lennox-Gastaut and Dravet syndromes), notably the influence on oxidative status, neurodegeneration, cellular protection, cognitive function, and physical performance. However, products containing CBD are not allowed to be marketed everywhere in the world, which may ultimately have a negative effect on health as a result of the uncontrolled CBD market. After the isolation of CBD follows the discovery of CB1 and CB2 receptors and the main enzymatic components (diacylglycerol lipase (DAG lipase), monoacyl glycerol lipase (MAGL), fatty acid amino hydrolase (FAAH)). At the same time, the antioxidant potential of CBD is due not only to the molecular structure but also to the fact that this compound increases the expression of the main endogenous antioxidant systems, superoxide dismutase (SOD), and glutathione peroxidase (GPx), through the nuclear complex erythroid 2-related factor (Nrf2)/Keep1. Regarding the role in the control of inflammation, this function is exercised by inhibiting (nuclear factor kappa B) NF-B, and also the genes that encode the expression of molecules with a pro-inflammatory role (cytokines and metalloproteinases). The other effects of CBD on cognitive function and physical performance should not be excluded. In conclusion, the CBD market needs to be regulated more thoroughly, given the previously listed properties, with the mention that the safety profile is a very good one.
10:24
A novel mechanism of cannabidiol in suppressing ovarian cancer . "IndyWatch Feed Health"
PMID: Environ Toxicol. 2023 May ;38(5):1118-1132. Epub 2023 Feb 22. PMID: 36810933 Abstract Title: A novel mechanism of cannabidiol in suppressing ovarian cancer through LAIR-1 mediated mitochondrial dysfunction and apoptosis. Abstract: Cannabidiol (CBD) is a nonpsychoactive cannabinoid compound. It has been shown that CBD can inhibit the proliferation of ovarian cancer cells, but the underlying specific mechanism is unclear. We previously presented the first evidence for the expression of leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1), a member of the immunosuppressive receptor family, in ovarian cancer cells. In the present study, we investigated the mechanism by which CBD inhibits the growth of SKOV3 and CAOV3 ovarian cancer cells, and we sought to understand the concurrent role of LAIR-1. In addition to inducing ovarian cancer cell cycle arrest and promoting cell apoptosis, CBD treatment significantly affected the expression of LAIR-1 and inhibited the PI3K/AKT/mTOR signaling axis and mitochondrial respiration in ovarian cancer cells. These changes were accompanied by an increase in ROS, loss of mitochondrial membrane potential, and suppression of mitochondrial respiration and aerobic glycolysis, thereby inducing abnormal or disturbed metabolism and reducing ATP production. A combined treatment with N-acetyl-l-cysteine and CBD indicated that a reduction in ROS production would restore PI3K/AKT/mTOR pathway signaling and ovarian cancer cell proliferation. We subsequently confirmed that the inhibitory effect of CBD on the PI3K/AKT/mTOR signal axis and mitochondrial bioenergy metabolism was attenuated by knockdown of LAIR-1. Our animal studies further support the in vivo anti-tumor activity of CBD and suggest its mechanism of action. In summary, the present findings confirm that CBD inhibits ovarian cancer cell growth by disrupting the LAIR-1-mediated interference with mitochondrial bioenergy metabolism and the PI3K/AKT/mTOR pathway. These results provide a new experimental basis for research into ovarian cancer treatment based on targeting LAIR-1 with CBD.
10:23
Topical 0.1% CBD reduced ulcer size and accelerated ulcer healing without side effects. "IndyWatch Feed Health"
PMID: BMC Complement Med Ther. 2023 Feb 20 ;23(1):57. Epub 2023 Feb 20. PMID: 36803360 Abstract Title: Efficacy and safety of topical 0.1% cannabidiol for managing recurrent aphthous ulcers: a randomized controlled trial. Abstract: BACKGROUND: Although topical steroids constitute the first-line therapy for recurrent aphthous ulcers (RAUs), their long-term use often leads to candidiasis. Although cannabidiol (CBD) can be an alternative for pharmacologically managing RAUs due to its analgesic and anti-inflammatory in vivo effects, there is a lack of clinical and safety trials concerning its use. The aim of this study was to evaluate the clinical safety and efficacy of topical 0.1% CBD for managing RAU.METHODS: A CBD patch test was performed on 100 healthy subjects. CBD was applied on the normal oral mucosa of 50 healthy subjects 3 times/day for 7 days. Oral examination, vital signs, and blood tests were performed pre- and post-CBD use. Another 69 RAU subjects randomly received one of three topical interventions: 0.1% CBD, 0.1% triamcinolone acetonide (TA), or placebo. These were applied on the ulcers 3 times/day for 7 days. The ulcer and erythematous size were measured on day 0, 2, 5, and 7. Pain ratings were recorded daily. The subjects rated their satisfaction with the intervention and completed a quality-of-life questionnaire (OHIP-14).RESULTS: None of the subjects exhibited allergic reactions or side effects. Their vital signs and blood parameters were stable before and after the 7-day CBD intervention. CBD and TA significantly reduced ulcer size more than placebo at all time points. The erythematous size reduction was higher in the CBD intervention than the placebo on day 2, while TA reduced the erythematous size at all time points. The pain score in the CBD group was lower compared with placebo on day 5, whereas TA reduced pain more than placebo on day 4, 5, and 7. The subjects receiving CBD reported higher satisfaction than placebo. However, the OHIP-14 scores were comparable among the interventions.CONCLUSIONS: Topical 0.1% CBD reduced ulcer size and accelerated ulcer healing without side effects. CBD exerted anti-inflammatory effects in the early stage and an analgesic effect in the late RAU stage. Thus, topical 0.1% CBD might be more appropriate for RAU patients who decline to take topical steroids, except for cases where CBD is contraindicated.TRIAL REGISTRATION: Thai Clinical Trials Registry (TCTR) Number TCTR20220802004. Retrospectively registered on 02/08/2022.
10:18
Scientific validation of cannabidiol for management of dog and cat diseases. "IndyWatch Feed Health"
PMID: Annu Rev Anim Biosci. 2023 Feb 15 ;11:227-246. PMID: 36790884 Abstract Title: Scientific Validation of Cannabidiol for Management of Dog and Cat Diseases. Abstract: Cannabidiol (CBD) is a non-psychotropic phytocannabinoid of the plantL. CBD is increasingly being explored as an alternative to conventional therapies to treat health disorders in dogs and cats. Mechanisms of action of CBD have been investigated mostly in rodents and in vitro and include modulation of CB1, CB2, 5-HT, GPR, and opioid receptors. In companion animals, CBD appears to have good bioavailability and safety profile with few side effects at physiological doses. Some dog studies have found CBD to improve clinical signs associated with osteoarthritis, pruritus, and epilepsy. However, further studies are needed to conclude a therapeutic action of CBD for each of these conditions, as well as for decreasing anxiety and aggression in dogs and cats. Herein, we summarize the available scientific evidence associated with the mechanisms of action of CBD, including pharmacokinetics, safety, regulation, and efficacy in ameliorating various health conditions in dogs and cats.
10:15
Cannabidiol regulates apoptosis and autophagy in inflammation and cancer. "IndyWatch Feed Health"
PMID: Front Pharmacol. 2023 ;14:1094020. Epub 2023 Jan 23. PMID: 36755953 Abstract Title: Cannabidiol regulates apoptosis and autophagy in inflammation and cancer: A review. Abstract: Cannabidiol (CBD) is a terpenoid naturally found in plants. The purified compound is used in the treatment of mental disorders because of its antidepressive, anxiolytic, and antiepileptic effects. CBD can affect the regulation of several pathophysiologic processes, including autophagy, cytokine secretion, apoptosis, and innate and adaptive immune responses. However, several authors have reported contradictory findings concerning the magnitude and direction of CBD-mediated effects. For example, CBD treatment can increase, decrease, or have no significant effect on autophagy and apoptosis. These variable results can be attributed to the differences in the biological models, cell types, and CBD concentration used in these studies. This review focuses on the mechanism of regulation of autophagy and apoptosis in inflammatory response and cancer by CBD. Further, we broadly elaborated on the prospects of using CBD as an anti-inflammatory agent and in cancer therapy in the future.
10:13
Inhalant cannabidiol impedes tumor growth through decreased tumor stemness. "IndyWatch Feed Health"
PMID: Hum Cell. 2023 May ;36(3):1204-1210. Epub 2023 Feb 3. PMID: 36737540 Abstract Title: Inhalant cannabidiol impedes tumor growth through decreased tumor stemness and impaired angiogenic switch in NCI-H1437-induced human lung cancer model. Abstract: Lung cancer remains the most chronic form of cancer and the leading cause of cancer mortality in the world. Despite significant improvements in the treatment of lung cancer, the current therapeutic interventions are only partially effective, necessitating the continued search for better, novel alternative treatments. Angiogenesis and cancer stem cells play a central role in the initiation and propagation of cancers. Tumor angiogenesis is triggered by an angiogenic switch when pro-angiogenic factors exceed anti-angiogenic components. Although many anti-angiogenic agents are used in cancer treatment, there are therapeutic limitations with significant side effects. In recent years, cannabinoids have been investigated extensively for their potential anti-neoplastic effects. Our previous findings showed that cannabidiol (CBD) could impede tumor growth in mouse models of melanoma and glioblastoma. Importantly, CBD has been suggested to possess anti-angiogenic activity. In this study, we tested, for the first time, inhalant CBD in the treatment of heterotopic lung cancer and whether such potential effects could reduce cancer stem cell numbers and inhibit tumor angiogenesis. We implanted NCI H1437 human lung cancer cells in nude mice and treated the mice with inhalant CBD or placebo. The outcomes were measured by tumor size and imaging, as well as by immunohistochemistry and flow cytometric analysis for CD44, VEGF, and P-selectin. Our findings showed that CBD decreased tumor growth rate and suppressed expression of CD44 and the angiogenic factors VEGF and P-selectin. These results suggest, for the first time, that inhalant CBD can impede lung cancer growth by suppressing CD44 and angiogenesis.
10:00
A Surprising Reason Why You May Need More Carbs in Your Diet "IndyWatch Feed Health"
In this interview, Georgi Dinkov and I continue our discussion about diet, diving into some of the finer details that can make or break your health. Dinkov is a student of Ray Peat, who passed away around Thanksgiving 2022, leaving behind a legacy of iconoclastic wisdom on how to optimize biological health.
For example, a ketogenic diet can be very useful initially when transitioning people who are metabolically inflexible, which is about 95% of the population of the United States. So, in the short term, the vast majority of people can benefit from going keto. However, if you continue in ketosis long term, you're going to run into problems.
Elevated Cortisol Leads to Central Obesity
As just one example, while weight loss is a typical response when going on a ketogenic diet, months later, maintaining that weight loss often becomes a struggle again. Dinkov experienced this firsthand. Once he started following Ray Peat's recommendations, he lost the weight again and kept it off.
"My take is it's an endocrine problem," Dinkov says. "So if you're struggling with weight you cannot lose, I think it's a good idea to do a blood work [panel] for the steroids Every single person that has been struggling with excessive weight that has emailed [me] their blood results, without exception, their cortisol is either high-normal or above the range, both the AM and the PM value.
Their thyroid is less than optimal, in fact, pretty bad for most people They're at the upper limit of normal. A very large number of people are basically hypothyroid I think we are eating foods that are lowering our metabolic rate. We're living an excessively stressful lifestyle.
That's probably not a surprise for anybody. Many people think, well, stress is good for you. It's good as a hormetic response in an acute situation, but not when you have chronically elevated cortisol. Every doctor will tell you if you have a chronic elevated cortisol, you will develop the so-called spectrum of Cushing syndrome
One of the defining features of elevated cortisol is that you have central obesity. So that, to me, is really the problem. We have higher than desirable levels of stress, suboptimal diet, and we're surrounded by a number of different endocrine disrupters which are now proven to reliably cause obesity in animal models, even in very small amounts. Most of those are found in plastics."
Why I Changed My Mind About Low-Carb
Diets
One of the foundational concepts of health tha...
How Excess Iron Raises Your Risk for Alzheimer's "IndyWatch Feed Health"
Editor's Note: This article is a reprint. It was originally published May 24, 2018.
While dietary iron is essential for optimal health1 being a key part of proteins and enzymes and playing an important role in energy production and the regulation of cell growth and differentiation, among other things too much iron in your body can have serious ramifications.2 One of the most important roles of iron is to provide hemoglobin (the protein in red blood cells) a mechanism through which it can bind to oxygen and carry it throughout your tissues.
Without proper oxygenation, your cells cannot function properly and eventually die. Common symptoms of insufficient iron include fatigue, decreased immunity or iron deficiency anemia, which can be serious if left untreated.
However, your body has a very limited capacity to excrete iron, which means it can build up in your tissues and organs. This is problematic, as iron is a potent oxidizer, capable of damaging tissues, including your vascular system and brain, thereby raising your risk for both heart disease and dementia.
Excess Iron 'Rusts' Your Brain
You're probably familiar with the fact that Alzheimer's disease is associated with a buildup of amyloid beta plaque in the brain. According to recent research3,4 from the Netherlands, buildup of iron, causing a rusting effect in the brain, also plays an important role and is common in most Alzheimer's patients. As noted by the authors:
"In the presence of the pathological hallmarks of [Alzheimer's disease], iron is accumulated within and around the amyloid-beta plaques and neurofibrillary tangles, mostly as ferrihydrite inside ferritin, hemosiderin and magnetite.
The co-localization of iron with amyloid-beta has been proposed to constitute a major source of toxicity. Indeed, in vitro, amyloid-beta has been shown to convert ferric iron to ferrous iron, which can act as a catalyst for the Fenton reaction to generate toxic free radicals, which in turn result in oxidative stress."
Addressing excess iron may therefore be an effective treatment option. A primary focus of conventional treatment so far has been to clear amyloid proteins, but while the approach seems logical, such attempts have met with limited success. Now, researchers suggest clearing out excess iron may be a more effective way to reduce damage and slow or p...
How to Build a Healthy Home "IndyWatch Feed Health"
Here, I interview Paula Baker-Laporte, principal architect at EcoNest Architecture1 in Ashland, Oregon, and co-author of Prescription for a Healthy House: A Practical Guide for Architects, Builders and Homeowners. She offers design and consulting services through EcoNestArchitecture.com.2
While overlooked by many, the materials used in the building of your home can have a significant impact on your health and Baker-Laporte can attest to this first-hand:
I graduated from the University of Toronto School of Architecture [in 1978] and then, shortly after, moved to Santa Fe. I was living in a home that was far from ideal. It was new.
There was a lot of formaldehyde in it. I didn't know what was happening to my health, I just knew it was going downhill. I started getting pneumonia, then double pneumonia, then fluorescein pneumonia every year.
I got sicker and sicker and moved from that house. The health problems still plagued me, but I didn't make the association. Then, my doctor, who was trying to help me and I was designing a house for her was getting progressively ill. That's when she discovered multiple chemical sensitivities.
There was nothing in either her medical education or my architectural education that would clue us into the fact that there was a connection between health and where we live.
Once she found out the cause of her ill health ... she called me up and said, I know what's wrong with you finally. It's wrong with me too and we've got to do this house differently. That was the start.
An Ever-Changing Landscape
The first edition of Prescriptions for a Healthy House was published 20 years ago. Its now on its fourth edition. The scene has changed, she says. More people are asking for a healthy house than before, and there are better materials available. So, a lot of things have gotten better, and then some things have gotten worse.
For example, when the book was first published, there was no wireless radiation to address. Shes also seeing more issues with mold these days, and some experts believe electromagnetic fields (EMFs) might play a role in that development.
In the past, most who sought Baker-Laportes services struggled with multiple chemical sensitivities. Today,...
09:51
Cannabidiol decreases intestinal inflammation in the ovariectomized murine model of postmenopause. "IndyWatch Feed Health"
PMID: Biomedicines. 2022 Dec 28 ;11(1). Epub 2022 Dec 28. PMID: 36672582 Abstract Title: Cannabidiol Decreases Intestinal Inflammation in the Ovariectomized Murine Model of Postmenopause. Abstract: Cannabidiol (CBD) (25 mg/kg peroral) treatment was shown to improve metabolic outcomes in ovariectomized (OVX) mice deficient in 17-estradiol (E2). Herein, CBD effects on intestinal and hepatic bile acids (BAs) and inflammation were investigated. Following RNA sequencing of colon tissues from vehicle (VEH)- or CBD-treated sham surgery (SS) or OVX mice (= 4 per group), differentially expressed genes (DEGs) were sorted in ShinyGO. Inflammatory response and bile secretion pathways were further analyzed. Colon content and hepatic BAs were quantified by LC-MS (= 8-10 samples/group). Gut organoids were treated with CBD (100, 250, 500M) with or without TNFand lipopolysaccharide (LPS) followed by mRNA extraction and qPCR to assess CBD-induced changes to inflammatory markers. The expression of 78 out of 114 inflammatory response pathway genes were reduced in CBD-treated OVX mice relative to vehicle (VEH)-treated OVX mice. In contrast, 63 of 111 inflammatory response pathway genes were increased in CBD-treated sham surgery (SS) mice compared to VEH-treated SS group and 71 of 121 genes were increased due to ovariectomy. CBD did not alter BA profiles in colon content or liver. CBD repressedandexpression in intestinal organoids in a dose-dependent manner. In conclusion, CBD suppressed colonic inflammatory gene expression in E2-deficient mice but was pro-inflammatory in E2-sufficient mice suggesting CBD activity in the intestine is E2-dependent.
09:47
Cannabidiol suppresses cytokine storm and protects against cardiac and renal iInjury associated with sepsis. "IndyWatch Feed Health"
PMID: Cannabis Cannabinoid Res. 2022 Dec 30. Epub 2022 Dec 30. PMID: 36594988 Abstract Title: Cannabidiol Suppresses Cytokine Storm and Protects Against Cardiac and Renal Injury Associated with Sepsis. Abstract: Cytokine release syndrome, also termed "cytokine storm," is the leading cause of morbidity and mortality among patients with various conditions such as sepsis. While cytokine storm is associated with multiple organ damage, acute cardiac and renal injury represents a hallmark of cytokine storm. Since recent reports have suggested that cannabidiol (CBD) may assist in the treatment of inflammatory diseases, our objective was to examine the effect of CBD on cytokine storm-induced cardiac and renal injury using the lipopolysaccharide (LPS)-induced sepsis mouse model.At 8 weeks of age, mice were randomly assigned to receive CBD (15mg/kg) or vehicle one hour before a single injection of either phosphate-buffered saline or LPS (10mg/kg) for an additional 24h.Our results show that CBD improves cardiac function and reduces renal injury in a mouse model of cytokine storm. Moreover, our data indicate that CBD significantly reduces systemic and renal inflammation to contribute to the improvements observed in a cytokine storm-model of cardiac and renal injury.Overall, the findings of this study suggest that CBD could be repurposed to reduce morbidity in patients with cytokine storm particularly in severe infections such as sepsis.
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08:41
Geoengineering Watch Global Alert News, June 3, 2023, #408 "IndyWatch Feed Health"
Dane Wigington GeoengineeringWatch.org "Seven
of the nine thresholds that allow for human life on Earth have
already been crossed", a breaking headline this week. Global
biodiversity loss has also been declared "significantly more
alarming than previously suspected". A new headline addressing the
state of the ozone layer admits that "surface UV radiation
continues to rise". As